{"id":"W3007605981","doi":"10.1093/jcag/gwz047.041","title":"A42 MICROBIAL METABOLISM OF DIETARY TRYPTOPHAN ENHANCES ARYL HYDROCARBON RECEPTOR ACTIVATION: IMPLICATIONS FOR IBD","year":2020,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Okanagan University College; University of British Columbia, Okanagan Campus; McMaster University","funders":"","keywords":"Aryl hydrocarbon receptor; Immune system; Colitis; Inflammatory bowel disease; Gut flora; Pathogenesis; Biology; Immunology; Mucin; Microbiology; Chemistry; Internal medicine; Medicine; Biochemistry; Transcription factor; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001267963,0.0003192657,0.0003063281,0.000290749,0.0001542849,0.0003532052,0.0001311269,0.0003562783,0.002358691],"category_scores_gemma":[0.0001141346,0.0001134027,0.0003838044,0.0001923566,0.0002206697,0.0001638064,0.0002639621,0.0004159771,0.0003812447],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002355206,"about_ca_system_score_gemma":0.0001606708,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000506677,"about_ca_topic_score_gemma":0.0005056958,"domain_scores_codex":[0.9998879,0.00002404475,0.000008392461,0.00002614779,0.00002365236,0.00002990919],"domain_scores_gemma":[0.9998586,0.00001147762,0.00005441624,0.000009768471,0.00001815696,0.00004756591],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001708718,0.00008430897,0.008384224,0.0001111924,0.00003159316,0.000160842,0.00001817299,0.00002845383,0.9858439,0.0000556674,0.0001145985,0.003458255],"study_design_scores_gemma":[0.0001840028,0.00395601,0.5237252,0.0001014928,0.0002193026,0.002321918,0.0003678853,0.001250239,0.4598309,0.0005158357,0.007501111,0.00002607],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884723,0.008308646,0.001318526,0.0002950354,0.00004861475,0.00002282913,0.0006257612,0.00004862505,0.0008596213],"genre_scores_gemma":[0.9958032,0.001766876,0.0008067893,0.0001206586,0.00002615516,0.00002319863,0.0004516776,0.000007911068,0.0009935424],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002358691,"threshold_uncertainty_score":0.007890642,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01193047380055199,"score_gpt":0.239017742166877,"score_spread":0.2270872683663251,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}