{"id":"W3007776995","doi":"10.18632/aging.102848","title":"Ancestral stress programs sex-specific biological aging trajectories and non-communicable disease risk","year":2020,"lang":"en","type":"article","venue":"Aging","topic":"Birth, Development, and Health","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Lethbridge","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Alberta Innovates","keywords":"Disease; Biology; Longevity; Epigenetics; Offspring; Physiology; Population; Bioinformatics; Medicine; Genetics; Internal medicine; Gene; Environmental health; Pregnancy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001706178,0.0002537716,0.0001942998,0.0002474359,0.0001915432,0.0002980735,0.000128546,0.0001650818,0.001568537],"category_scores_gemma":[0.0002826082,0.0001163992,0.0002415115,0.0001348581,0.0002245452,0.0001557287,0.0004408745,0.0003683292,0.0001166968],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002625931,"about_ca_system_score_gemma":0.0003190703,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002039687,"about_ca_topic_score_gemma":0.005130615,"domain_scores_codex":[0.9999151,0.00001285464,0.000003418774,0.00003808664,0.00001391349,0.0000164688],"domain_scores_gemma":[0.9998668,0.00001518809,0.00005075076,0.00001657195,0.00002123156,0.00002934776],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00131057,0.0001645106,0.3266415,0.000243238,0.0004551498,0.0006144661,0.0005541358,0.0011178,0.5780785,0.002266366,0.001301288,0.08725241],"study_design_scores_gemma":[0.00000922327,0.0003827036,0.9600291,0.00004469784,0.0001658239,0.0004301732,0.0002269362,0.001324669,0.03204986,0.001482385,0.00382814,0.00002633886],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915541,0.00156783,0.003987787,0.0001882567,0.00003678026,0.000008449865,0.001480081,0.00008100394,0.001095866],"genre_scores_gemma":[0.9947459,0.001017066,0.001951251,0.00009226182,0.00001050427,0.00002043507,0.0006250814,0.00002695244,0.001510674],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002039687,"threshold_uncertainty_score":0.005247235,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06898382228050723,"score_gpt":0.3058346928132052,"score_spread":0.236850870532698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}