{"id":"W3007897623","doi":"10.1093/jcag/gwz047.016","title":"A17 ASSOCIATION BETWEEN HOST INFLAMMATION-RELATED PROTEOMICS AND GUT MICROBIOME IN HEALTHY FIRST-DEGREE RELATIVES OF CROHN’S DISEASE PATIENTS","year":2020,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital; University of Toronto","funders":"","keywords":"Microbiome; Disease; Immunology; Inflammation; Biology; Tumor necrosis factor alpha; Immune system; Crohn's disease; Gut flora; Metagenomics; Systemic inflammation; Asymptomatic; Proteomics; Medicine; Genetics; Internal medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003387259,0.0003619425,0.0003765767,0.0006325069,0.0005312992,0.0004253506,0.0001842016,0.0004524612,0.002565328],"category_scores_gemma":[0.001761691,0.0001933931,0.00033339,0.0005122737,0.0002083661,0.0002701913,0.0003105297,0.0004091877,0.0002506017],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002091081,"about_ca_system_score_gemma":0.0001412238,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00215537,"about_ca_topic_score_gemma":0.001697824,"domain_scores_codex":[0.9996551,0.00007321029,0.00003918574,0.0001180283,0.00004484069,0.00006962741],"domain_scores_gemma":[0.9989977,0.0002448472,0.0003653028,0.0000667217,0.0000975772,0.0002278752],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002812508,0.00002812182,0.996894,0.00001241887,0.00004108365,0.0003333282,0.00009666982,0.00001740861,0.001114674,0.00001199404,0.00008694084,0.001082059],"study_design_scores_gemma":[0.000005572017,0.0001189191,0.9982899,0.000005534179,0.00003392922,0.0009542113,0.000173022,0.0000972946,0.0001662071,0.00002043391,0.0001320588,0.000002883723],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995412,0.0001690104,0.00004169298,0.00002461846,0.000005595568,0.000001131532,0.00007748954,0.000002084993,0.0001372475],"genre_scores_gemma":[0.999781,0.00002839996,0.00003767155,0.00001184876,0.0000049481,0.000001184373,0.00005126151,9.655226e-7,0.00008266615],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002565328,"threshold_uncertainty_score":0.008581877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007280898344658151,"score_gpt":0.2037113094704742,"score_spread":0.196430411125816,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}