{"id":"W3007898063","doi":"10.1016/j.mehy.2020.109645","title":"Multiple sclerosis is a systemic venous vasculopathy: A single unifying mechanism","year":2020,"lang":"en","type":"article","venue":"Medical Hypotheses","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sunnybrook Health Science Centre; Health Sciences Centre; University of Toronto","funders":"","keywords":"Medicine; Pathology; Multiple sclerosis; Disease; Cerebrospinal fluid; Antigen; Immunology; Central nervous system; Inflammation; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008340307,0.0003242926,0.0009071585,0.0001468515,0.0002345477,0.00006991937,0.000454813,0.000235221,0.001169851],"category_scores_gemma":[0.02314435,0.0002485953,0.0003116103,0.000595087,0.0002600133,0.0001003764,0.0004089252,0.000580202,0.000581244],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001620037,"about_ca_system_score_gemma":0.0002683073,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000994815,"about_ca_topic_score_gemma":0.00001662207,"domain_scores_codex":[0.994926,0.0002359432,0.0006282816,0.0007123243,0.002761291,0.0007361782],"domain_scores_gemma":[0.9965919,0.001235629,0.0001261882,0.0005250968,0.0002682083,0.001252984],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001466652,0.004072706,0.03780989,0.004370103,0.002107242,0.001739047,0.0275647,0.00001404991,0.5604168,0.0005128555,0.02304551,0.3368805],"study_design_scores_gemma":[0.06106218,0.0207998,0.1462565,0.02822065,0.002186068,0.001990722,0.03465725,0.1098465,0.4379412,0.002166626,0.1488025,0.006070043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9577873,0.003634939,0.004971339,0.02871724,0.0002838245,0.001545881,0.00006762792,0.0006050223,0.002386862],"genre_scores_gemma":[0.9902208,0.001208215,0.001060475,0.006445338,0.0007156241,0.0001172602,0.000008025319,0.00007532787,0.0001488647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3308105,"threshold_uncertainty_score":0.9999966,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.173249203272138,"score_gpt":0.2917881571817186,"score_spread":0.1185389539095806,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}