{"id":"W3007935195","doi":"10.1016/j.humimm.2020.02.010","title":"Assessment of a poly-epitope candidate vaccine against Hepatitis B, C, and poliovirus in interaction with monocyte-derived dendritic cells: An ex-vivo study","year":2020,"lang":"en","type":"article","venue":"Human Immunology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network; Michener Institute","funders":"Shahid Beheshti University of Medical Sciences","keywords":"Epitope; Immunogenicity; Ex vivo; Antigen; Antigenicity; T cell; HBsAg; In silico; Immune system; Antigen-presenting cell; Virology; Biology; Immunology; In vivo; Hepatitis B virus; Virus; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003700605,0.000264467,0.0002454375,0.00008550698,0.0001463986,0.0002783145,0.0001716773,0.0002755577,0.0008985013],"category_scores_gemma":[0.0001296116,0.00009136278,0.0001924753,0.00008329254,0.0001455079,0.0002214215,0.0001027141,0.0005403305,0.0002018706],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001168449,"about_ca_system_score_gemma":0.0001424294,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000277757,"about_ca_topic_score_gemma":0.0003348313,"domain_scores_codex":[0.9998645,0.00005141395,0.000005607593,0.00002025842,0.00002403673,0.00003415947],"domain_scores_gemma":[0.9999219,0.0000311779,0.000008931646,0.000008144022,0.00001398442,0.00001583085],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004985895,0.0003371606,0.000164446,0.00004052078,0.000004645573,0.00004288272,0.00002151273,0.0001329035,0.997663,0.00004618452,0.00001811804,0.001030035],"study_design_scores_gemma":[0.0001320598,0.009742552,0.003086881,0.000007708474,0.00004244912,0.0002223303,0.00009441292,0.002436905,0.9828803,0.00005259995,0.001297259,0.000004606343],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997735,0.0003753995,0.001418552,0.00002779014,0.00002059508,0.00004294594,0.0000500537,0.000004886752,0.0003246681],"genre_scores_gemma":[0.996792,0.000436653,0.001517714,0.00004130616,0.00001608032,0.00004066142,0.0001441709,0.00000390966,0.001007558],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008985013,"threshold_uncertainty_score":0.003005803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02821222099393275,"score_gpt":0.3171221716520075,"score_spread":0.2889099506580748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}