{"id":"W3008165957","doi":"10.1097/ccm.0000000000004247","title":"Epigenetics of Sepsis","year":2020,"lang":"en","type":"article","venue":"Critical Care Medicine","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University of Manitoba; McMaster University; William Osler Health System; Niagara Health System; St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Epigenetics; Sepsis; DNA methylation; Medicine; Histone; Immunology; Organ dysfunction; Bioinformatics; Biology; Gene expression; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001223768,0.0003734115,0.0006506211,0.001065004,0.0003910181,0.001547937,0.0003545857,0.0008994936,0.003840135],"category_scores_gemma":[0.00367655,0.0001612399,0.0007035288,0.001039257,0.001146003,0.001279324,0.001049426,0.001117964,0.0004925858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007709769,"about_ca_system_score_gemma":0.002159903,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008982616,"about_ca_topic_score_gemma":0.001011261,"domain_scores_codex":[0.9992,0.0004068495,0.0001057945,0.0000975296,0.000138707,0.00005115322],"domain_scores_gemma":[0.9985121,0.0007823777,0.0003068031,0.00005068065,0.0002743838,0.00007376439],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0007634849,0.0001120637,0.0100862,0.06338579,0.001256839,0.002221541,0.004544296,0.001390845,0.01579899,0.06570858,0.07179449,0.7629369],"study_design_scores_gemma":[0.0001452588,0.0005782559,0.0336967,0.0317635,0.001036559,0.00588717,0.002842727,0.000530762,0.007129984,0.0495457,0.866694,0.0001493975],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01075407,0.9497928,0.003093519,0.01958819,0.002203885,0.00008132324,0.0008994862,0.00005999472,0.01352676],"genre_scores_gemma":[0.1403139,0.8428467,0.002707578,0.007177034,0.002482591,0.0001909742,0.0007255959,0.00002112593,0.003534461],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003840135,"threshold_uncertainty_score":0.01284659,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02829052900312425,"score_gpt":0.3260245812846542,"score_spread":0.29773405228153,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}