{"id":"W3008232610","doi":"10.1128/msystems.00629-19","title":"Intranasal Bacterial Therapeutics Reduce Colonization by the Respiratory Pathogen Mannheimia haemolytica in Dairy Calves","year":2020,"lang":"en","type":"article","venue":"mSystems","topic":"Microbial infections and disease research","field":"Immunology and Microbiology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada; Government of Canada; Alberta Agriculture and Forestry","keywords":"Bovine respiratory disease; Pathogen; Colonization; Nasal administration; Antibiotics; Microbiology; Biology; Dairy cattle; Immunology; Animal science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002727941,0.0001228099,0.0001838414,0.00004325986,0.0001820765,0.00005925618,0.0001990061,0.0001913152,0.0002777697],"category_scores_gemma":[0.00004289361,0.00009109776,0.00005428261,0.0002409711,0.0001493379,0.00005082104,0.00005878699,0.0002585635,0.0002494202],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005318085,"about_ca_system_score_gemma":0.0001227333,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001519862,"about_ca_topic_score_gemma":0.0000362046,"domain_scores_codex":[0.9986238,0.0005347372,0.0002873056,0.0002388889,0.00004070879,0.0002744911],"domain_scores_gemma":[0.999573,0.00008180293,0.00005886837,0.0001994957,0.0000499731,0.00003688093],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001839363,0.00006813311,0.0008819384,0.00002685358,0.00006737269,0.000006705415,0.0005414128,0.000009785409,0.949218,0.0002249555,0.04796535,0.0008054944],"study_design_scores_gemma":[0.001612143,0.0002407623,0.0006447337,0.00003956762,0.00004364958,0.00003710056,0.0005164534,0.00008814992,0.07555255,0.00001429493,0.9209849,0.0002256437],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895543,0.005338798,0.0002094809,0.002463962,0.0007839723,0.0006820212,0.0001947563,0.00007560784,0.0006970593],"genre_scores_gemma":[0.998417,0.00006615535,0.000002161778,0.0008998741,0.000165318,0.00003994502,0.0001552254,0.00001787428,0.0002364882],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8736655,"threshold_uncertainty_score":0.3714859,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04757397429949757,"score_gpt":0.2885847320389626,"score_spread":0.2410107577394651,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}