{"id":"W3008240165","doi":"10.1002/stem.3165","title":"Differential effects of heat-inactivated, secretome-deficient MSC and metabolically active MSC in sepsis and allogenic heart transplantation","year":2020,"lang":"en","type":"article","venue":"Stem Cells","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Deutsche Forschungsgemeinschaft","keywords":"Mesenchymal stem cell; Sepsis; Biology; Transplantation; Immunology; CD16; Immune system; CD8; Monocyte; Cancer research; CD3; Medicine; Cell biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001344097,0.0001906259,0.0005658965,0.0001459974,0.00004112011,0.00001720204,0.00006188406,0.0001258033,0.00009687129],"category_scores_gemma":[0.00002856983,0.0001598379,0.0000733483,0.0003257855,0.00009723829,0.00006203402,0.00005438858,0.0003210089,0.0000114092],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004350109,"about_ca_system_score_gemma":0.00006362129,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001450918,"about_ca_topic_score_gemma":0.00001647235,"domain_scores_codex":[0.9982758,0.0002343546,0.0003064869,0.0004264259,0.0004369323,0.0003200061],"domain_scores_gemma":[0.9990235,0.0004039956,0.00004661385,0.0001443624,0.00006117457,0.0003203829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001122083,0.0001115948,0.004318319,0.001954927,0.00008205304,0.00007488628,0.0021756,0.000007699948,0.9882346,0.00002367462,0.00003904623,0.00185551],"study_design_scores_gemma":[0.002857517,0.000739119,0.04374867,0.0002023232,0.00015273,0.00002426556,0.0003363493,0.0008874203,0.9506429,0.000006031502,0.0002633446,0.0001393588],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970175,0.0006281889,0.0001870224,0.0007006614,0.00006288963,0.001038751,0.00002550847,0.00002351345,0.0003159835],"genre_scores_gemma":[0.9989502,0.0006044122,0.0000908162,0.0001423212,0.00004014853,0.00002651867,0.00001303302,0.0000241098,0.0001084205],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03943035,"threshold_uncertainty_score":0.6518001,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01507793828970957,"score_gpt":0.2607395608947899,"score_spread":0.2456616226050803,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}