{"id":"W3008296453","doi":"10.1021/acs.jnatprod.9b00721","title":"A Meroisoprenoid, Heptenolides, and <i>C</i>-Benzylated Flavonoids from <i>Sphaerocoryne gracilis</i> ssp. <i>gracilis</i>","year":2020,"lang":"en","type":"article","venue":"Journal of Natural Products","topic":"Traditional and Medicinal Uses of Annonaceae","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Australian Research Council; Sveriges Regering; Vetenskapsrådet","keywords":"Bark (sound); Plasmodium falciparum; Cytotoxicity; In vitro; Chemistry; Stereochemistry; HEK 293 cells; Biology; Botany; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001813322,0.000254687,0.0003672948,0.00004656793,0.00008470259,0.00003783569,0.0002854377,0.0001339669,0.0000136518],"category_scores_gemma":[0.000508031,0.0001991984,0.000131721,0.0001938191,0.0001464593,0.00004199813,0.00009840566,0.0004971165,0.000009300546],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001384134,"about_ca_system_score_gemma":0.000152256,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000198077,"about_ca_topic_score_gemma":0.000006608737,"domain_scores_codex":[0.9984115,0.00006618832,0.0004888567,0.0003959273,0.0003732898,0.0002641933],"domain_scores_gemma":[0.9986644,0.00003143118,0.000334317,0.0001853899,0.0004822785,0.0003022122],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009173898,0.00006626246,0.0001818398,0.00004770189,0.0001635837,0.00007872833,0.0001547989,0.00001520179,0.9431543,0.00002264862,0.05168342,0.003514066],"study_design_scores_gemma":[0.002606203,0.00170157,0.003225782,0.00009790264,0.0001841589,0.0004969423,0.0001844243,0.00002372371,0.7029572,0.0004309522,0.2876461,0.0004451107],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9491208,0.03521085,0.00004112232,0.01469867,0.0005600739,0.0001585197,0.00007498641,0.00001520686,0.0001198024],"genre_scores_gemma":[0.9892675,0.001509882,0.001395704,0.004977233,0.002488381,0.000001792037,0.0001364247,0.0000239986,0.0001990602],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2401972,"threshold_uncertainty_score":0.8123075,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01004609512404907,"score_gpt":0.2022353110136707,"score_spread":0.1921892158896216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}