{"id":"W3008296453","doi":"10.1021/acs.jnatprod.9b00721","title":"A Meroisoprenoid, Heptenolides, and <i>C</i>-Benzylated Flavonoids from <i>Sphaerocoryne gracilis</i> ssp. <i>gracilis</i>","year":2020,"lang":"en","type":"article","venue":"Journal of Natural Products","topic":"Traditional and Medicinal Uses of Annonaceae","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Australian Research Council; Sveriges Regering; Vetenskapsrådet","keywords":"Bark (sound); Plasmodium falciparum; Cytotoxicity; In vitro; Chemistry; Stereochemistry; HEK 293 cells; Biology; Botany; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005812579,0.0004095891,0.0001282957,0.0002102059,0.0001409792,0.0001665029,0.0001200603,0.0001339315,0.00298295],"category_scores_gemma":[0.0001034069,0.00007115397,0.0001700233,0.0002139387,0.0001396774,0.0002051442,0.0001448041,0.0003239524,0.0004387933],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001092956,"about_ca_system_score_gemma":0.0001942172,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005550705,"about_ca_topic_score_gemma":0.001166624,"domain_scores_codex":[0.9999645,0.000005736972,0.000004103991,0.000008540549,0.000009176097,0.000008064482],"domain_scores_gemma":[0.9999394,0.00001213976,0.00001341383,0.000007693339,0.0000109359,0.0000163272],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001578683,0.000008236543,0.0001133857,0.0000769578,0.000005689184,0.00003895615,0.00001496481,0.00002825417,0.997526,0.00005661415,0.00003519456,0.001937854],"study_design_scores_gemma":[0.00002267761,0.0005107999,0.007966686,0.00002450195,0.00004083095,0.0004166682,0.00007378893,0.000144884,0.9779121,0.00009365536,0.01278264,0.00001079037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9820218,0.004520516,0.002210199,0.0001248789,0.000058691,0.00005528683,0.002700338,0.00007761373,0.008230659],"genre_scores_gemma":[0.9824085,0.002110491,0.003241512,0.0001042218,0.00002029796,0.00003002543,0.004935677,0.00002835537,0.007120839],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00298295,"threshold_uncertainty_score":0.00997895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01004609512404907,"score_gpt":0.2022353110136707,"score_spread":0.1921892158896216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}