{"id":"W3008336266","doi":"10.1039/c9ra10663d","title":"Design, synthesis, and biological evaluation of novel arylcarboxamide derivatives as anti-tubercular agents","year":2020,"lang":"en","type":"article","venue":"RSC Advances","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Bentley (Canada)","funders":"National Heart, Lung, and Blood Institute; Australian Research Council; National Institutes of Health; Curtin University of Technology; Division of Intramural Research, National Institute of Allergy and Infectious Diseases","keywords":"Antimycobacterial; Indole test; Combinatorial chemistry; Chemistry; Carboxamide; Stereochemistry; Tuberculosis; Mycobacterium tuberculosis; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003148183,0.0004690379,0.0004236876,0.0002480933,0.0001864571,0.0003000343,0.0004782797,0.0003576637,0.001575124],"category_scores_gemma":[0.0002765724,0.000212185,0.000355158,0.000296188,0.0001976162,0.0002219674,0.0001968807,0.0004842632,0.0005872678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002622256,"about_ca_system_score_gemma":0.0002814013,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004169229,"about_ca_topic_score_gemma":0.001107574,"domain_scores_codex":[0.9998355,0.00003529829,0.00002045243,0.00003186864,0.00004212313,0.00003469183],"domain_scores_gemma":[0.999887,0.00001334466,0.0000317648,0.00001400383,0.00002872148,0.00002525825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003571023,0.000267415,0.0001451153,0.0004420792,0.00002463057,0.0003645022,0.00005076263,0.001452904,0.9810759,0.0004966904,0.0002775485,0.01504532],"study_design_scores_gemma":[0.0004018337,0.006304246,0.001476406,0.00005085367,0.0000924118,0.0006846017,0.00003815551,0.001929141,0.9687151,0.0001176557,0.02014657,0.00004301505],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9456609,0.01456978,0.02514866,0.0003099032,0.0002032422,0.001671048,0.001292722,0.0002836315,0.01086008],"genre_scores_gemma":[0.9572195,0.00975736,0.02476554,0.000152664,0.00004775776,0.0005606416,0.000987537,0.00003379608,0.006475197],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001575124,"threshold_uncertainty_score":0.005269289,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1761417823990277,"score_gpt":0.4017525513278972,"score_spread":0.2256107689288695,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}