{"id":"W3008413005","doi":"10.1016/j.bbamem.2020.183250","title":"Mechanisms of Co, Ni, and Mn toxicity: From exposure and homeostasis to their interactions with and impact on lipids and biomembranes","year":2020,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Biomembranes","topic":"Trace Elements in Health","field":"Nursing","cited_by":107,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Toxicity; Metal toxicity; Chemistry; Homeostasis; Oxidative stress; Membrane; Biochemistry; Lipid metabolism; Biophysics; Cell biology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004702164,0.0009526664,0.001625103,0.00195142,0.000223035,0.0009658741,0.000923339,0.001098578,0.001618362],"category_scores_gemma":[0.0005369178,0.0002453472,0.0004614193,0.001863461,0.0005170348,0.001055531,0.0007412254,0.0009374919,0.0008854442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007281201,"about_ca_system_score_gemma":0.001569319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003405887,"about_ca_topic_score_gemma":0.005499986,"domain_scores_codex":[0.9998348,0.00002486875,0.00002926917,0.00003040751,0.00006425542,0.00001630586],"domain_scores_gemma":[0.9997764,0.00009360178,0.00004155638,0.000006681138,0.00006800725,0.00001360955],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001122433,0.00006488793,0.0004823605,0.03022829,0.0001756196,0.0001733319,0.0001068068,0.0004156045,0.003597484,0.004782655,0.01435453,0.9455062],"study_design_scores_gemma":[0.00002028348,0.000128949,0.00181391,0.006465973,0.0003014698,0.001221345,0.0001964959,0.0001299295,0.001896179,0.004274677,0.9835162,0.00003469365],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001163896,0.9991763,0.0001076112,0.000184173,0.00006764962,0.000002154001,0.00001332777,0.000004111467,0.0003282552],"genre_scores_gemma":[0.0005598127,0.9989669,0.0001083706,0.00007455184,0.00004241533,0.000003416461,0.00001255252,5.74157e-7,0.0002312864],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003405887,"threshold_uncertainty_score":0.006772161,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03217779310073977,"score_gpt":0.3339078601830882,"score_spread":0.3017300670823484,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}