{"id":"W3008523340","doi":"10.1146/annurev-clinpsy-050718-095530","title":"Epigenetics, Development, and Psychopathology","year":2020,"lang":"en","type":"review","venue":"Annual Review of Clinical Psychology","topic":"Early Childhood Education and Development","field":"Social Sciences","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Canadian Institute for Advanced Research","funders":"Natural Sciences and Engineering Research Council of Canada; Jacobs Foundation; Canada First Research Excellence Fund; Agency for Science, Technology and Research; McGill University; Medical Research Council; Canadian Institute for Advanced Research; National Medical Research Council; Hope for Depression Research Foundation","keywords":"Epigenetics; Psychopathology; Psychology; Epigenesis; Translational research; Developmental psychopathology; Neuroscience; Relevance (law); Mental health; Cognitive science; Biology; Genetics; Clinical psychology; Psychiatry; DNA methylation; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004974309,0.0005720194,0.0006388352,0.001263679,0.0003954368,0.001034119,0.0004624678,0.0009999454,0.003288536],"category_scores_gemma":[0.0008108094,0.0001406516,0.0003069973,0.001203113,0.001190896,0.0009047381,0.0009227159,0.001310638,0.0007340866],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000757486,"about_ca_system_score_gemma":0.002269411,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002449685,"about_ca_topic_score_gemma":0.003526132,"domain_scores_codex":[0.9998314,0.00005783661,0.00001614479,0.00002895706,0.00004547555,0.00002016342],"domain_scores_gemma":[0.9997188,0.0001734225,0.00002883465,0.000009454325,0.00004149015,0.00002792337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003956487,0.00004978607,0.0008000382,0.009509335,0.0000875745,0.0002455762,0.0004200964,0.0002358325,0.001237437,0.02396526,0.02265636,0.9407531],"study_design_scores_gemma":[0.00001024416,0.00007983443,0.006256094,0.006924184,0.0000959769,0.001780326,0.0004909387,0.00006284098,0.0004604251,0.01640055,0.9674112,0.00002744392],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002676304,0.9964644,0.0001530321,0.001031616,0.0002398353,0.000003474554,0.00001402383,0.000007768093,0.001818203],"genre_scores_gemma":[0.002236115,0.996669,0.0001159648,0.0002256662,0.0001902808,0.000005796203,0.00001375628,0.000001236419,0.0005421826],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003288536,"threshold_uncertainty_score":0.01100123,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2620847484840154,"score_gpt":0.601661792260913,"score_spread":0.3395770437768976,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}