{"id":"W3008568612","doi":"10.1016/j.ijpharm.2020.119152","title":"Halloysite nanotube-embedded microparticles for intestine-targeted co-delivery of biopharmaceuticals","year":2020,"lang":"en","type":"article","venue":"International Journal of Pharmaceutics","topic":"Oral and gingival health research","field":"Health Professions","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"University of Alberta; Alberta Innovates; Alberta Innovates - Technology Futures; Bill and Melinda Gates Foundation","keywords":"Halloysite; Drug delivery; Chemistry; Microparticle; Drug carrier; Dispersity; Mucus; Controlled release; Biophysics; Chemical engineering; Chromatography; Nanotechnology; Materials science; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001232667,0.0001958137,0.000229633,0.0001755339,0.0001598343,0.0002195928,0.0002227062,0.0005733515,0.0006648109],"category_scores_gemma":[0.0001636617,0.0001293594,0.0002299943,0.0001095071,0.0001343928,0.000253007,0.000278913,0.0003223885,0.0003048376],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001698844,"about_ca_system_score_gemma":0.0001172366,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002803676,"about_ca_topic_score_gemma":0.0007594541,"domain_scores_codex":[0.9998792,0.00001578851,0.000009484796,0.00003125939,0.00003762026,0.00002646819],"domain_scores_gemma":[0.9999273,0.00001662676,0.00001945314,0.000006004468,0.00001447602,0.00001618846],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005309149,0.0000225738,0.00004943761,0.00004191336,0.000004781165,0.00005513428,0.00001029806,0.0001150163,0.99739,0.00009889204,0.00004861177,0.002110322],"study_design_scores_gemma":[0.000009259914,0.0002351011,0.0005131906,0.000004293458,0.00001423321,0.0000725478,0.00001371249,0.001934473,0.9959413,0.00002162149,0.001232718,0.00000763071],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865855,0.001893251,0.009201395,0.0001135672,0.0001147346,0.00006040269,0.0001124178,0.0001313419,0.001787267],"genre_scores_gemma":[0.9912094,0.0005903515,0.005736663,0.00004649516,0.00002065616,0.00004052233,0.00006112145,0.00001613802,0.002278677],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006648109,"threshold_uncertainty_score":0.002223969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2994395522070612,"score_gpt":0.5761938288612402,"score_spread":0.276754276654179,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}