{"id":"W3008652560","doi":"10.1101/2020.02.28.965087","title":"Alternative splicing of COQ-2 determines the choice between ubiquinone and rhodoquinone biosynthesis in helminths","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Coenzyme Q10 studies and effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; National Institutes of Health; Agencia Nacional de Investigación e Innovación","keywords":"Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004209223,0.0004509288,0.0006468266,0.0001035766,0.00009854975,0.00005232607,0.0004787005,0.0003247731,0.000003364316],"category_scores_gemma":[0.0004779822,0.0003892371,0.0001284269,0.0002362148,0.0002269779,0.000006383194,0.001301857,0.0003670379,0.000002932518],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004102489,"about_ca_system_score_gemma":0.0001190558,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004333051,"about_ca_topic_score_gemma":0.00005355695,"domain_scores_codex":[0.9979335,0.0001761512,0.00046738,0.0008387758,0.0002027024,0.000381457],"domain_scores_gemma":[0.9983765,0.0001932475,0.000378815,0.0007449464,0.0001774835,0.0001289431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004734741,0.00003831564,0.04029068,0.0003692029,0.0002490307,0.00001340373,0.00002804551,0.00002583893,0.958557,0.00001724232,0.000354237,0.000009713598],"study_design_scores_gemma":[0.0004111296,0.0001560775,0.1559387,0.000338385,0.0001180499,2.233742e-8,0.00000870026,0.0001248925,0.8407441,0.000001326593,0.001738747,0.000419847],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954032,0.00268685,0.0002979981,0.0006104633,0.0002300482,0.0005820821,0.0001587078,0.00002531085,0.000005305417],"genre_scores_gemma":[0.997173,0.001243742,0.0004494116,0.0001555031,0.0008122919,0.00009318902,7.042804e-7,0.00006974513,0.000002430339],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1178129,"threshold_uncertainty_score":0.9998559,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01755691223827582,"score_gpt":0.2424350027542812,"score_spread":0.2248780905160054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}