{"id":"W3008705236","doi":"10.1200/jco.19.01836","title":"Liberal Versus Restrictive Red Blood Cell Transfusion Thresholds in Hematopoietic Cell Transplantation: A Randomized, Open Label, Phase III, Noninferiority Trial","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Blood transfusion and management","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Juravinski Hospital; London Health Sciences Centre; University of Saskatchewan; University of Ottawa; University of Calgary; Alberta Cancer Foundation; Baker Hughes (Canada); Foothills Medical Centre; Ottawa Hospital","funders":"Canadian Blood Services; London Health Sciences Centre; Canadian Institutes of Health Research; Hamilton Health Sciences","keywords":"Medicine; Hematopoietic cell; Open label; Hematopoietic stem cell transplantation; Transplantation; Red blood cell; Blood transfusion; Randomized controlled trial; Oncology; Haematopoiesis; Internal medicine; Surgery; Immunology; Stem cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003833033,0.001450445,0.002549149,0.0004254275,0.0005512699,0.001313496,0.001180914,0.002345015,0.003597149],"category_scores_gemma":[0.004321792,0.000577519,0.001429536,0.0004942139,0.001850289,0.001243645,0.0004673831,0.002790619,0.0004041697],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00105444,"about_ca_system_score_gemma":0.001893856,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001387027,"about_ca_topic_score_gemma":0.003034813,"domain_scores_codex":[0.9976469,0.001506669,0.0001761207,0.0002938004,0.0001800739,0.0001965095],"domain_scores_gemma":[0.9971589,0.00115978,0.0007870317,0.0001925203,0.0001490968,0.0005527108],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.97815,0.007490028,0.0006743115,0.0004041557,0.0006215704,0.00002004719,0.00003389854,0.0002497055,0.001059142,0.00009817187,0.0003091919,0.01088987],"study_design_scores_gemma":[0.9460462,0.05191665,0.0008298927,0.00003509181,0.0003000092,0.00001352191,0.00001542726,0.0002582675,0.0002301644,0.0001496937,0.0001957206,0.000009325178],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9837427,0.005586174,0.001018958,0.001165011,0.0006546745,0.005725211,0.0004167687,0.0000991165,0.001591374],"genre_scores_gemma":[0.9886767,0.001553998,0.002323779,0.00143044,0.0005127582,0.004481536,0.0002097552,0.000009912685,0.0008010949],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003833033,"threshold_uncertainty_score":0.0202713,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1660273247058247,"score_gpt":0.460340397095794,"score_spread":0.2943130723899693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}