{"id":"W3008780324","doi":"10.1053/j.gastro.2020.02.027","title":"Closing the Stable Door After the Horse Has Bolted: Should We Be Treating People With Immune-Tolerant Chronic Hepatitis B to Prevent Hepatocellular Carcinoma?","year":2020,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital","funders":"Gilead Sciences; AbbVie; Bristol-Myers Squibb","keywords":"Medicine; Hepatocellular carcinoma; Internal medicine; Cirrhosis; Population; Liver cancer; Chronic hepatitis; Gastroenterology; Family medicine; Virus; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002713899,0.0004002036,0.0007269633,0.00006531875,0.0004428088,0.00006506698,0.0002942537,0.00008335833,0.0002485975],"category_scores_gemma":[0.0000752488,0.0002261291,0.0001778596,0.0002617917,0.0002708701,0.00008152916,0.0003441869,0.0005320278,0.00005511483],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002330208,"about_ca_system_score_gemma":0.0001458282,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.006656539,"about_ca_topic_score_gemma":0.02690391,"domain_scores_codex":[0.9972308,0.0003179074,0.0005346484,0.0005660789,0.0004118441,0.0009387381],"domain_scores_gemma":[0.9987529,0.00009412935,0.0001613342,0.0006376231,0.0001181487,0.0002358433],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001508705,0.0001196945,0.9828491,0.0001184568,0.0002971567,0.0002568295,0.01002483,0.000114509,0.00216894,0.000007141959,0.002135049,0.0003995764],"study_design_scores_gemma":[0.003529311,0.00975924,0.9490111,0.0003945909,0.0009050221,0.0005478973,0.0009616596,0.01062711,0.003010519,0.00001096337,0.02088605,0.000356557],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8952867,0.001990207,0.001351992,0.09960737,0.0001351252,0.001423605,0.00005524129,0.0000794244,0.00007038748],"genre_scores_gemma":[0.9875454,0.0002446948,0.0004424993,0.01049984,0.0004058742,0.0006356025,0.00002316228,0.00007391038,0.0001289753],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09225879,"threshold_uncertainty_score":0.9999582,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02890365156322622,"score_gpt":0.2455620919936036,"score_spread":0.2166584404303774,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}