{"id":"W3008886783","doi":"10.1093/jcag/gwz047.218","title":"A219 PROTECTIVE EFFECTS OF AKKERMANSIA MUCINIPHILA ON INTESTINAL BARRIER FUNCTION AND INFLAMMATION","year":2020,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Akkermansia muciniphila; Colitis; Microbiology; Inflammation; Myeloperoxidase; Mucin; Immunology; Inflammatory bowel disease; Goblet cell; Biology; Akkermansia; Barrier function; Gut flora; Medicine; Bacteria; Epithelium; Disease; Pathology; Lactobacillus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001054184,0.000519593,0.0003780804,0.000378258,0.0002052997,0.0002938403,0.0001993475,0.0004424017,0.002055708],"category_scores_gemma":[0.0001098531,0.00009800693,0.0003417875,0.0001999566,0.0001993973,0.0002798175,0.0002251182,0.0005540884,0.0004140449],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001403757,"about_ca_system_score_gemma":0.0002179399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000510378,"about_ca_topic_score_gemma":0.0004667611,"domain_scores_codex":[0.9998785,0.00001962118,0.00001372516,0.00001955139,0.0000270678,0.00004154988],"domain_scores_gemma":[0.9998286,0.00001465509,0.00005104686,0.00001178876,0.00002168149,0.00007220275],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006427347,0.0001919323,0.0003354001,0.0001183541,0.000009360524,0.00007486951,0.0000103576,0.00003059052,0.9967198,0.00002904201,0.00007039513,0.00176723],"study_design_scores_gemma":[0.0001233003,0.007562504,0.0308057,0.00005536941,0.00008662088,0.0006055264,0.0001391249,0.0008805644,0.9532135,0.0001180312,0.006390271,0.00001962888],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938284,0.003604969,0.0004755159,0.0002003233,0.0001001818,0.00003643625,0.0005126221,0.00007290569,0.001168647],"genre_scores_gemma":[0.9936805,0.001856491,0.001033042,0.0001149153,0.00005719563,0.00004549582,0.0005943251,0.000008803548,0.002609284],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002055708,"threshold_uncertainty_score":0.006877005,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004205228163776531,"score_gpt":0.1959442674030677,"score_spread":0.1917390392392912,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}