{"id":"W3009043580","doi":"10.1016/s0140-6736(19)33137-x","title":"Considerations and methods for placebo controls in surgical trials (ASPIRE guidelines)","year":2020,"lang":"en","type":"review","venue":"The Lancet","topic":"Pain Management and Placebo Effect","field":"Neuroscience","cited_by":94,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre; Western University","funders":"Medical Research Council; Oxford Health NHS Foundation Trust; University of Oxford; University of Bristol; Department of Health and Social Care; University Hospitals Bristol NHS Foundation Trust; Cancer Research UK; National Institute for Health and Care Research","keywords":"Placebo; Medicine; Context (archaeology); Psychological intervention; Checklist; Clinical trial; Randomized controlled trial; Clinical study design; Intensive care medicine; Physical therapy; Alternative medicine; Surgery; Psychology; Psychiatry; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.02638779,0.0002911864,0.003269396,0.00008046795,0.0001307167,0.0001733007,0.0003421343,0.0001371085,0.00004917709],"category_scores_gemma":[0.06174491,0.0001646187,0.0003192106,0.0002102822,0.00008292096,0.00004972846,0.0001062224,0.0003206087,0.00002440697],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002201762,"about_ca_system_score_gemma":0.00009231396,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003748076,"about_ca_topic_score_gemma":0.0000047727,"domain_scores_codex":[0.9824305,0.01576986,0.0009190634,0.0004597378,0.0001187758,0.0003020616],"domain_scores_gemma":[0.9135629,0.08564395,0.0003629128,0.0003595115,0.00001849005,0.00005224966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001146781,0.000006050181,5.568591e-7,0.001834107,0.00003483747,0.00002734283,0.00002563357,0.000003703879,0.00001413578,0.0109959,0.02412979,0.9628133],"study_design_scores_gemma":[0.001780427,0.00002640149,1.55412e-7,0.0009220936,0.0003242817,0.00002498345,0.000002086497,0.002269089,0.000008979233,0.002380366,0.9920803,0.0001808693],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[2.243752e-7,0.9803724,0.005076572,0.005719459,0.0002590145,0.005056418,0.0001758541,0.00006724246,0.003272814],"genre_scores_gemma":[0.000003664916,0.9916516,0.003970289,0.001951487,0.001194398,0.0009120146,0.00001700247,0.0000261251,0.0002734119],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9679505,"threshold_uncertainty_score":0.9461584,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4653835765691064,"score_gpt":0.5365957283110369,"score_spread":0.07121215174193046,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}