{"id":"W3009229072","doi":"10.1002/med.21667","title":"Purine and pyrimidine transporters of pathogenic protozoa – conduits for therapeutic agents","year":2020,"lang":"en","type":"review","venue":"Medicinal Research Reviews","topic":"Pharmacological Effects and Toxicity Studies","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Purine; Biology; Purine metabolism; Transporter; Protozoa; Pyrimidine; Biochemistry; Microbiology; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000191965,0.0005262641,0.0008542805,0.001625355,0.0001916061,0.000870759,0.0004242344,0.0006236801,0.004425551],"category_scores_gemma":[0.0002501703,0.0001944403,0.0003603959,0.001372732,0.0001910161,0.0008226721,0.0003563607,0.0007959767,0.001959306],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002969828,"about_ca_system_score_gemma":0.0005515674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005391165,"about_ca_topic_score_gemma":0.001071042,"domain_scores_codex":[0.9998982,0.00001479171,0.00001466951,0.00001866386,0.00004060866,0.00001307362],"domain_scores_gemma":[0.9999145,0.00002986245,0.00001504795,0.000002695863,0.00003005542,0.000007859649],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001669491,0.0001252276,0.0002444854,0.0430814,0.0001289941,0.0005243513,0.0001418207,0.0005711623,0.02580327,0.007930372,0.02137611,0.8999059],"study_design_scores_gemma":[0.00001112689,0.0001284967,0.0008401694,0.002216933,0.0001204083,0.00129022,0.00006141244,0.000141067,0.002822623,0.001349853,0.9910018,0.00001587171],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006268646,0.9962741,0.0003183243,0.0001726891,0.0001435532,0.000009541967,0.00006160808,0.00001570855,0.002377665],"genre_scores_gemma":[0.002412599,0.9954247,0.0003908567,0.0001131939,0.00008933571,0.000008583595,0.00008549907,0.00000240062,0.001472888],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004425551,"threshold_uncertainty_score":0.01480496,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.6275596394903283,"score_gpt":0.5854518768196766,"score_spread":0.04210776267065175,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}