{"id":"W3009237397","doi":"10.1080/21645515.2020.1717183","title":"Protection of outbred mice against a vaginal challenge by a <i>Chlamydia trachomatis</i> serovar E recombinant major outer membrane protein vaccine is dependent on phosphate substitution in the adjuvant","year":2020,"lang":"en","type":"article","venue":"Human Vaccines & Immunotherapeutics","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sanofi (Canada)","funders":"Sanofi Pasteur","keywords":"Chlamydia trachomatis; Adjuvant; Microbiology; Serotype; Biology; Bacterial outer membrane; Recombinant DNA; Virology; Pathogen; Antibody; Vaccination; Titer; Immunology; Escherichia coli; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000756124,0.001262355,0.0006095245,0.0008563771,0.0003047861,0.0005756828,0.0004897997,0.001052034,0.002466738],"category_scores_gemma":[0.0003992083,0.000411683,0.0005717109,0.0001952298,0.00055346,0.0004793121,0.0003352044,0.001582257,0.0005478293],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002224439,"about_ca_system_score_gemma":0.0003086852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002901634,"about_ca_topic_score_gemma":0.0005232552,"domain_scores_codex":[0.9996431,0.00007185916,0.00003130654,0.00008704327,0.00005936712,0.0001073173],"domain_scores_gemma":[0.9986817,0.0002367244,0.0004730243,0.0002312585,0.00008673617,0.0002904721],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001383093,0.0007347904,0.000693018,0.00005168133,0.00002223953,0.0001045835,0.00004546492,0.00007581025,0.9953038,0.0001121366,0.00007241478,0.001401166],"study_design_scores_gemma":[0.0001653278,0.01211877,0.01261893,0.00003663959,0.00006846678,0.0007890548,0.00008052523,0.0007641136,0.9715793,0.0001172004,0.001643619,0.00001815537],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956347,0.0004469343,0.001587882,0.0001300138,0.00006465695,0.00006558076,0.0004822246,0.0001360333,0.001451878],"genre_scores_gemma":[0.9886413,0.0006139974,0.002630911,0.0001913477,0.00004396014,0.0000842091,0.001287256,0.0001026095,0.006404422],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002466738,"threshold_uncertainty_score":0.008252084,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03583404858345659,"score_gpt":0.2751310632820033,"score_spread":0.2392970146985467,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}