{"id":"W3009317060","doi":"10.1016/j.oret.2020.02.015","title":"Impact of Systemic Chemotherapy and Delayed Enucleation on Survival of Children with Advanced Intraocular Retinoblastoma","year":2020,"lang":"en","type":"article","venue":"Ophthalmology Retina","topic":"Ocular Disorders and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Krembil Foundation; University of Alberta; Hospital for Sick Children; University of Ottawa","funders":"Princess Margaret Cancer Foundation","keywords":"Enucleation; Medicine; Carboplatin; Chemotherapy; Histopathology; Surgery; Retinoblastoma; Etoposide; Pathology; Cisplatin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004809089,0.0001500955,0.0002450965,0.00002184324,0.00002333136,0.000002777064,0.00008272162,0.0001195347,0.00001639031],"category_scores_gemma":[0.00002551703,0.0001169189,0.00007674806,0.00007283223,0.0001099945,0.00000266715,0.00002707031,0.00005215714,0.000001208268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007002655,"about_ca_system_score_gemma":0.00003116333,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002509287,"about_ca_topic_score_gemma":5.860066e-7,"domain_scores_codex":[0.9992822,0.00006880123,0.0001620375,0.0002775335,0.0000805857,0.0001288126],"domain_scores_gemma":[0.9995269,0.000008976741,0.000161402,0.00018947,0.00005738227,0.00005583983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00227552,0.0001434588,0.6470957,0.00002783099,0.0005515712,0.00001435928,0.0001104639,0.0001485229,0.3483192,0.00002203036,0.00001669461,0.00127462],"study_design_scores_gemma":[0.005110758,0.02541055,0.7918336,0.00007647662,0.0001054261,0.0008354364,0.000100568,0.00006258361,0.1761192,0.00002279691,0.00001046492,0.0003121642],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988217,0.00045602,0.00005596069,0.00004836846,0.00001199505,0.000249502,0.00002982708,0.000004798779,0.0003218704],"genre_scores_gemma":[0.999474,0.0001296526,0.0002305691,0.00001573017,0.0000198039,0.000006239115,0.00009003427,0.00002284944,0.00001112505],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1721999,"threshold_uncertainty_score":0.4767814,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006006170419585361,"score_gpt":0.2484915581437547,"score_spread":0.2424853877241693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}