{"id":"W3009378833","doi":"10.1053/j.gastro.2020.02.058","title":"Safety and Efficacy of 48 Weeks REP 2139 or REP 2165, Tenofovir Disoproxil, and Pegylated Interferon Alfa-2a in Patients With Chronic HBV Infection Naïve to Nucleos(t)ide Therapy","year":2020,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":232,"is_retracted":false,"has_abstract":true,"ca_institutions":"Quebec Rehabilitation Research Network","funders":"","keywords":"HBsAg; Pegylated interferon; Medicine; Gastroenterology; Internal medicine; Tolerability; Combination therapy; Hepatitis B virus; Immunology; Virology; Pharmacology; Chronic hepatitis; Virus; Adverse effect; Ribavirin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001161361,0.000685769,0.001111963,0.0002320162,0.0003210427,0.0003950617,0.0003417316,0.0007919178,0.001582518],"category_scores_gemma":[0.001563218,0.0003533179,0.0008655418,0.0001812538,0.0004446297,0.0005641163,0.0002077902,0.0009991642,0.0003669495],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004496483,"about_ca_system_score_gemma":0.0004216057,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002907141,"about_ca_topic_score_gemma":0.0003903442,"domain_scores_codex":[0.9993191,0.0003540968,0.00005684539,0.0001137757,0.00008124684,0.00007505074],"domain_scores_gemma":[0.9990423,0.0001996632,0.0003622844,0.00008355489,0.00004713712,0.0002649642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8287828,0.02650949,0.02706237,0.0003466221,0.0007945921,0.0003011126,0.0002425986,0.001017413,0.02890518,0.00005324867,0.0003993626,0.08558516],"study_design_scores_gemma":[0.124978,0.7820935,0.08200551,0.00003772299,0.000533659,0.0004250525,0.00007898061,0.001223276,0.007445133,0.00008968917,0.001050515,0.00003891257],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999159,0.0004680733,0.0000522997,0.00003577461,0.00001086251,0.00005230304,0.00004995115,0.000008858116,0.0001629382],"genre_scores_gemma":[0.9991093,0.000174836,0.0001495675,0.0000566425,0.00003440316,0.0001303934,0.0001116528,0.000002062534,0.0002311002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001582518,"threshold_uncertainty_score":0.006141961,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01190625091230059,"score_gpt":0.245618649372204,"score_spread":0.2337123984599034,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}