{"id":"W3009378833","doi":"10.1053/j.gastro.2020.02.058","title":"Safety and Efficacy of 48 Weeks REP 2139 or REP 2165, Tenofovir Disoproxil, and Pegylated Interferon Alfa-2a in Patients With Chronic HBV Infection Naïve to Nucleos(t)ide Therapy","year":2020,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":232,"is_retracted":false,"has_abstract":true,"ca_institutions":"Quebec Rehabilitation Research Network","funders":"","keywords":"HBsAg; Pegylated interferon; Medicine; Gastroenterology; Internal medicine; Tolerability; Combination therapy; Hepatitis B virus; Immunology; Virology; Pharmacology; Chronic hepatitis; Virus; Adverse effect; Ribavirin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001291319,0.0002483609,0.0006512817,0.000152085,0.00005667539,0.000006928303,0.00006272124,0.0000960776,0.00005722634],"category_scores_gemma":[0.0001854625,0.0001832221,0.00003717762,0.000188115,0.000201492,0.00008268574,0.0001624132,0.0002597155,0.000007834501],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001299278,"about_ca_system_score_gemma":0.00003456249,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008411132,"about_ca_topic_score_gemma":0.004920439,"domain_scores_codex":[0.9983031,0.0001360736,0.0005010712,0.0005055739,0.0001575157,0.0003966452],"domain_scores_gemma":[0.9992698,0.00004793869,0.0001641885,0.0002377693,0.0001011253,0.0001791754],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0309803,0.0002500219,0.9579691,0.00008536836,0.0001801956,0.00002411718,0.001490849,0.00001706281,0.0009710641,0.000002548682,0.0002060285,0.00782331],"study_design_scores_gemma":[0.01193226,0.02449421,0.9620334,0.0001600983,0.00004893218,0.00002301705,0.00002708226,0.0000981445,0.0001546004,0.00000253871,0.00093342,0.00009229439],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953828,0.0001080944,0.0002263252,0.00307712,0.00008900616,0.001000863,0.00002442134,0.00005233627,0.00003905288],"genre_scores_gemma":[0.9975097,0.0004600188,0.0002185636,0.00163018,0.00006187919,0.0000290095,0.00003075882,0.00003625474,0.00002359022],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02424419,"threshold_uncertainty_score":0.7471579,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01190625091230059,"score_gpt":0.245618649372204,"score_spread":0.2337123984599034,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}