{"id":"W3009539044","doi":"10.1017/s0031182020000426","title":"Assessing anthelmintic resistance risk in the post-genomic era: a proof-of-concept study assessing the potential for widespread benzimidazole-resistant gastrointestinal nematodes in North American cattle and bison","year":2020,"lang":"en","type":"article","venue":"Parasitology","topic":"Helminth infection and control","field":"Veterinary","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Agriculture and Forestry","keywords":"Biology; Anthelmintic; Benzimidazole; Drug resistance; Amplicon; Resistance (ecology); Genetics; Biotechnology; Gene; Zoology; Polymerase chain reaction; Ecology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005458463,0.0002206292,0.0004916918,0.0001072417,0.0002376006,0.0001383345,0.0002892322,0.00003468317,0.000006427982],"category_scores_gemma":[0.0006789515,0.0001525658,0.00007634758,0.0003802473,0.0003485861,0.0001710179,0.00006016836,0.0004045551,0.000001579582],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004396276,"about_ca_system_score_gemma":0.0001186411,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009826724,"about_ca_topic_score_gemma":0.007601569,"domain_scores_codex":[0.9973871,0.001068429,0.0005819232,0.000421564,0.0001463351,0.0003946359],"domain_scores_gemma":[0.9981289,0.001050115,0.0004213694,0.0002635582,0.00007869644,0.00005738115],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001203105,0.0003795104,0.9768803,0.0000713172,0.0000423682,0.0001701599,0.006605501,0.0004328317,0.006235085,0.00003923065,0.00002246131,0.007918115],"study_design_scores_gemma":[0.001221001,0.00124866,0.9763488,0.00004834928,0.00007815849,0.0001636509,0.01505652,0.005464691,0.0001637912,0.000031626,0.00002017146,0.0001546511],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923196,0.0001860725,0.004259849,0.001889199,0.0000818374,0.001157847,0.00002478081,0.00002463572,0.00005619923],"genre_scores_gemma":[0.998766,0.000001818772,0.0006738135,0.000267349,0.0000791049,0.0001813772,0.000005860041,0.00002301187,0.000001689248],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008451018,"threshold_uncertainty_score":0.6221453,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03697070401457692,"score_gpt":0.3587943794393361,"score_spread":0.3218236754247592,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}