{"id":"W3009652969","doi":"10.1128/msphere.00883-19","title":"Culture-Confirmed Invasive Meningococcal Disease in Canada, 2010 to 2014: Characterization of Serogroup B <i>Neisseria meningitidis</i> Strains and Their Predicted Coverage by the 4CMenB Vaccine","year":2020,"lang":"en","type":"article","venue":"mSphere","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada","funders":"Wellcome Trust","keywords":"Neisseria meningitidis; Meningococcal disease; Meningococcal vaccine; Neisseriaceae; Microbiology; Virology; Medicine; Bacterial meningitis; Biology; Meningitis; Bacteria; Antibiotics; Pediatrics; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004855393,0.0001723303,0.0002487193,0.00001411957,0.000096572,0.00001957591,0.0001269921,0.00008393507,0.0007267405],"category_scores_gemma":[0.00004392984,0.0001171916,0.0000280675,0.0001448467,0.0000226446,0.00009013261,0.00006706816,0.0001601702,0.000007264534],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003643083,"about_ca_system_score_gemma":0.0001932662,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.09507449,"about_ca_topic_score_gemma":0.1827313,"domain_scores_codex":[0.9991702,0.0001129519,0.0002667274,0.0002305501,0.00001446191,0.0002050695],"domain_scores_gemma":[0.9995919,0.00004018353,0.0001026419,0.0001402151,0.0000501865,0.00007490179],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002341019,0.00003354709,0.03338559,0.00002325873,0.00006432656,8.051422e-7,0.0009723697,0.000008934627,0.9524845,0.00002192753,0.01225126,0.0005193799],"study_design_scores_gemma":[0.002377692,0.0003293571,0.7697448,0.00006693533,0.00005116807,0.000009465374,0.000823138,0.00003479823,0.1923708,0.00001710163,0.03387393,0.0003008888],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960353,0.0003109291,0.00007324107,0.001670863,0.000264007,0.0004554282,0.001126908,0.00002280606,0.00004050448],"genre_scores_gemma":[0.9983141,0.0001011348,0.0000033237,0.0004164078,0.00004253976,0.00004590575,0.0008345357,0.00001386266,0.0002282135],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7601137,"threshold_uncertainty_score":0.9109515,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006697881543629932,"score_gpt":0.1873608544353354,"score_spread":0.1806629728917054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}