{"id":"W3009706603","doi":"10.1136/bmjdrc-2019-000923","title":"Increased placental mitochondrial fusion in gestational diabetes mellitus: an adaptive mechanism to optimize feto-placental metabolic homeostasis?","year":2020,"lang":"en","type":"article","venue":"BMJ Open Diabetes Research & Care","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; University of Toronto; Lunenfeld-Tanenbaum Research Institute","funders":"Institute of Human Development, Child and Youth Health; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Suomen Kulttuurirahasto; Canadian Institutes of Health Research; Biomedicum Helsinki-säätiö; National Institutes of Health","keywords":"Placenta; Mitochondrion; Ceramide; mitochondrial fusion; Gestational diabetes; Endocrinology; Biology; Oxidative stress; Internal medicine; Offspring; Placentation; Fetus; Pregnancy; Medicine; Cell biology; Gestation; Apoptosis; Mitochondrial DNA; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002991996,0.0003304393,0.000283512,0.0002811755,0.0001756059,0.0004391799,0.0003048204,0.0004207595,0.001063361],"category_scores_gemma":[0.0003232765,0.00009913306,0.0002635389,0.0002908103,0.0004761118,0.0004081678,0.0004674788,0.0006828278,0.0001353153],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007404658,"about_ca_system_score_gemma":0.0002564525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004710221,"about_ca_topic_score_gemma":0.0004150411,"domain_scores_codex":[0.9998634,0.00002507123,0.00001196346,0.00003003133,0.00003419936,0.00003532143],"domain_scores_gemma":[0.9998605,0.0000136845,0.00006692794,0.00001306795,0.00001567482,0.00002994936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001476939,0.00005926651,0.0216372,0.0007211833,0.00009120858,0.003329019,0.0003073019,0.0003644282,0.9375327,0.002209523,0.0004474296,0.03182384],"study_design_scores_gemma":[0.0001071433,0.001869199,0.2836306,0.0003498007,0.0002583601,0.02161342,0.001600705,0.003081056,0.6592915,0.005564066,0.02254918,0.00008511108],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9483891,0.03543811,0.0104658,0.002186099,0.0002146517,0.00003768734,0.0004567069,0.0001453057,0.002666468],"genre_scores_gemma":[0.9877015,0.008907095,0.002266187,0.00016918,0.00004698075,0.00001887947,0.0002026488,0.000009265009,0.0006782952],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001063361,"threshold_uncertainty_score":0.005372524,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09434910996158258,"score_gpt":0.3920202938738609,"score_spread":0.2976711839122784,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}