{"id":"W3009870983","doi":"10.1158/1538-7445.sabcs19-p1-03-11","title":"Abstract P1-03-11: In vivo rapid discovery of tumor suppressors in breast cancer","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute","funders":"","keywords":"Cancer; Biology; Cancer research; Suppressor; Breast cancer; Tumor suppressor gene; Epigenetics; Mammary tumor; Gene; Mutation; Cancer cell; Genetics; Carcinogenesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005711684,0.0004326903,0.000392798,0.0003722883,0.0001641072,0.0005111695,0.0003759698,0.0006024268,0.003416636],"category_scores_gemma":[0.0002016494,0.0002654572,0.000358605,0.0001980012,0.000301794,0.0001938472,0.0004207715,0.001218098,0.00126291],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003143495,"about_ca_system_score_gemma":0.0003175627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003802579,"about_ca_topic_score_gemma":0.0005279223,"domain_scores_codex":[0.999663,0.00005211339,0.00002230622,0.00008549484,0.0001229356,0.00005412422],"domain_scores_gemma":[0.999791,0.00004388296,0.00004509367,0.00003529614,0.00002272252,0.00006204339],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009891753,0.00006624544,0.0001193086,0.00002606685,0.000007843008,0.0000307523,0.000008067052,0.0001317648,0.9966809,0.0001938306,0.0003088163,0.002327411],"study_design_scores_gemma":[0.00003891791,0.0006545576,0.001017,0.000004059751,0.00001589061,0.0001766604,0.000006815605,0.001544399,0.9907625,0.00005771085,0.005716375,0.00000493223],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9105142,0.003057292,0.06474439,0.000819361,0.0004149365,0.0009238155,0.005240443,0.003389382,0.01089628],"genre_scores_gemma":[0.9345912,0.001486897,0.0381838,0.0003775219,0.00004828788,0.0004879672,0.004701698,0.0005526103,0.01957019],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003416636,"threshold_uncertainty_score":0.01142979,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02831245265789243,"score_gpt":0.375782520404754,"score_spread":0.3474700677468616,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}