{"id":"W3009891869","doi":"10.1158/1538-7445.sabcs19-gs4-01","title":"Abstract GS4-01: Ten-year results from NRG Oncology/NSABP B-42: A randomized, double-blinded, placebo-controlled clinical trial of extended adjuvant endocrine therapy with letrozole (L) in postmenopausal women with hormone-receptor+ breast cancer (BC) who have completed previous adjuvant therapy with an aromatase inhibitor (AI)","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Medicine; Letrozole; Internal medicine; Clinical endpoint; Statistical significance; Breast cancer; Oncology; Placebo; Tamoxifen; Hormonal therapy; Randomized controlled trial; Cancer; Gastroenterology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003156268,0.002767147,0.003575196,0.0007825565,0.0004730406,0.001185577,0.001387099,0.002581991,0.01160854],"category_scores_gemma":[0.002357425,0.0007922699,0.002496164,0.0006108296,0.001729225,0.001068968,0.000640766,0.003652367,0.001543432],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007899672,"about_ca_system_score_gemma":0.001735401,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001405736,"about_ca_topic_score_gemma":0.002325438,"domain_scores_codex":[0.9985914,0.0009519699,0.00008160872,0.0001313217,0.00007956916,0.0001641817],"domain_scores_gemma":[0.9987025,0.0003357912,0.0002864412,0.0001239562,0.00007896046,0.0004723199],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9885328,0.003312029,0.0001615608,0.0002848428,0.0005350594,0.00002231897,0.00001455418,0.0001645178,0.001745598,0.00003371476,0.0004443591,0.004748723],"study_design_scores_gemma":[0.9517694,0.04645165,0.0007155336,0.00001611662,0.0003615555,0.00001077461,0.00000808959,0.00007348294,0.0002436069,0.00004710206,0.0002950391,0.000007666246],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9777229,0.005567261,0.0006161067,0.001372132,0.0007558271,0.00608111,0.004353095,0.0002956837,0.003235942],"genre_scores_gemma":[0.9734545,0.003183473,0.001739918,0.002298207,0.00084506,0.006290974,0.004538657,0.00006008963,0.007589126],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01160854,"threshold_uncertainty_score":0.03883445,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09348842831903145,"score_gpt":0.4190237873823928,"score_spread":0.3255353590633614,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}