{"id":"W3010027759","doi":"10.1158/1538-7445.sabcs19-p1-19-16","title":"Abstract P1-19-16: Long-term pooled safety analysis of palbociclib in combination with endocrine therapy for hormone receptor-positive/human epidermal growth factor receptor 2–negative advanced breast cancer: An updated analysis","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Spinal Cord Injury BC","funders":"","keywords":"Palbociclib; Fulvestrant; Letrozole; Medicine; Internal medicine; Breast cancer; Cancer; Adverse effect; Oncology; Placebo; Metastatic breast cancer; Gynecology; Gastroenterology; Estrogen receptor; Tamoxifen; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02062889,0.002157181,0.005233335,0.002356609,0.0002779893,0.002565082,0.001209636,0.0009852288,0.004484036],"category_scores_gemma":[0.01887883,0.0007707716,0.01601883,0.002634217,0.0004144635,0.001460694,0.001266568,0.001723383,0.0008119677],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001354213,"about_ca_system_score_gemma":0.002241675,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001131209,"about_ca_topic_score_gemma":0.001835054,"domain_scores_codex":[0.9879874,0.006316099,0.001567872,0.001458869,0.00232321,0.0003465482],"domain_scores_gemma":[0.9865885,0.004292169,0.005349074,0.001324517,0.002022323,0.000423386],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"observational","study_design_scores_codex":[0.2076941,0.0006954515,0.04461079,0.0163386,0.6142617,0.0004185899,0.0001094562,0.006781308,0.008808706,0.0003026984,0.01133615,0.0886425],"study_design_scores_gemma":[0.07631551,0.03085538,0.1880804,0.001493272,0.6602588,0.001084657,0.0001096147,0.005484548,0.006843199,0.001054709,0.028178,0.0002419015],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6701063,0.2110787,0.01664831,0.001647608,0.001058175,0.007125098,0.08248011,0.0009821899,0.008873397],"genre_scores_gemma":[0.9431942,0.01628051,0.004381005,0.001313185,0.0008412178,0.003104791,0.02739316,0.0002190649,0.003272777],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02062889,"threshold_uncertainty_score":0.1090973,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04543092689725916,"score_gpt":0.3934009876766021,"score_spread":0.3479700607793429,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}