{"id":"W3010044425","doi":"10.3174/ajnr.a6481","title":"Ratio of T1-Weighted to T2-Weighted Signal Intensity as a Measure of Tissue Integrity: Comparison with Magnetization Transfer Ratio in Patients with Multiple Sclerosis","year":2020,"lang":"en","type":"article","venue":"American Journal of Neuroradiology","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"Sanofi Genzyme; Multiple Sclerosis International Federation; Generalitat de Catalunya; Multiple Sclerosis Society; Instituto de Salud Carlos III; Teva Pharmaceutical Industries; Red Española de Esclerosis Múltiple; Biogen; Bayer; Celgene; Sanofi","keywords":"Magnetization transfer; White matter; Multiple sclerosis; Medicine; Correlation; Nuclear magnetic resonance; Myelin; Magnetic resonance imaging; Intensity (physics); Nuclear medicine; Pathology; Radiology; Internal medicine; Physics; Central nervous system; Mathematics; Optics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008126426,0.0003767305,0.000393436,0.001548597,0.0002364384,0.0004691574,0.0002478985,0.0006393304,0.001381904],"category_scores_gemma":[0.002515911,0.0001500709,0.000238341,0.00059691,0.0003208768,0.000579136,0.0002582823,0.0003041606,0.0003135247],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001720315,"about_ca_system_score_gemma":0.0001236249,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005894717,"about_ca_topic_score_gemma":0.0006446239,"domain_scores_codex":[0.9997591,0.00006713812,0.00005191422,0.00006109707,0.00003928547,0.0000213624],"domain_scores_gemma":[0.9990013,0.0002995248,0.0003822481,0.00005174383,0.0001271002,0.0001380421],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0014492,0.00008851558,0.9872265,0.0000564465,0.0002001603,0.000478174,0.0001701388,0.0001581672,0.00490937,0.0000250809,0.0001203844,0.005117808],"study_design_scores_gemma":[0.00003717581,0.0006434338,0.9947037,0.00000831862,0.0001052267,0.002024858,0.0001505689,0.0007623093,0.001363995,0.00006906412,0.0001220393,0.000009266887],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990907,0.0003502667,0.0001152012,0.00003209117,0.00000488924,0.000006723584,0.00006897582,0.000009583062,0.0003217218],"genre_scores_gemma":[0.9996498,0.0000523226,0.0001365749,0.00001037761,0.0000100632,0.000004285016,0.00006810078,0.000002431442,0.00006605239],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001548597,"threshold_uncertainty_score":0.004622936,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04575680522828481,"score_gpt":0.2768176218433934,"score_spread":0.2310608166151086,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}