{"id":"W3010122357","doi":"10.1101/2020.03.01.971416","title":"Interspecific Hybrids Show a Reduced Adaptive Potential Under DNA Damaging Conditions","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Evolution and Genetic Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; PROTEO","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Fonds de recherche du Québec – Nature et technologies; Fundación Bancaria Caixa d'Estalvis i Pensions de Barcelona","keywords":"Hybrid; Biology; Adaptation (eye); Saccharomyces cerevisiae; Genetics; DNA damage; DNA; Adaptive evolution; Adaptability; Yeast; Experimental evolution; Evolutionary biology; Gene; Botany; Ecology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002046637,0.0002491346,0.0002367804,0.0003964497,0.0001858329,0.0003460898,0.0002436404,0.0003808335,0.003272867],"category_scores_gemma":[0.0002370562,0.0001457209,0.000262803,0.0002234112,0.0002143091,0.0001640634,0.000500225,0.0006531927,0.0004435509],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001671236,"about_ca_system_score_gemma":0.00005529596,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002374292,"about_ca_topic_score_gemma":0.0003381443,"domain_scores_codex":[0.9997562,0.00003846706,0.00002018098,0.00008132913,0.00006526378,0.00003857841],"domain_scores_gemma":[0.9995905,0.000126987,0.00008006107,0.0000891801,0.00004575493,0.00006751643],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007149234,0.00002632179,0.00130104,0.00001562119,0.00002242993,0.00004826331,0.00003115195,0.00007143004,0.9970728,0.0001001055,0.00002129446,0.001218051],"study_design_scores_gemma":[0.00002346218,0.0006898837,0.1206903,0.00001012878,0.000100321,0.001424474,0.0002908983,0.001398177,0.8704235,0.0006068797,0.004307092,0.00003493679],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961479,0.000320231,0.001759187,0.00003559721,0.00001712896,0.000006512862,0.0002606682,0.00005177462,0.001401155],"genre_scores_gemma":[0.9961092,0.00009976824,0.0009573828,0.0000506091,0.000006739172,0.00001673375,0.0005573841,0.00005257928,0.002149704],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003272867,"threshold_uncertainty_score":0.01094884,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01422710548237025,"score_gpt":0.2312525701960584,"score_spread":0.2170254647136881,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}