{"id":"W3010161595","doi":"10.1200/jco.2007.25.18_suppl.1003","title":"A randomized, double-blind phase II study of the oral tyrosine kinase inhibitor (TKI) axitinib (AG-013736) in combination with docetaxel (DOC) compared to DOC plus placebo (PL) in metastatic breast cancer (MBC)","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Cancer Treatment and Pharmacology","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Notre-Dame","funders":"","keywords":"Medicine; Docetaxel; Internal medicine; Taxane; Adverse effect; Gastroenterology; Placebo; Nausea; Neutropenia; Febrile neutropenia; Stomatitis; Metastatic breast cancer; Anthracycline; Chemotherapy; Breast cancer; Pharmacology; Oncology; Cancer; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007192982,0.0002742034,0.003303928,0.0005134026,0.00006068752,0.000009981035,0.0002365855,0.0001851214,0.00024435],"category_scores_gemma":[0.000485329,0.0001591308,0.0003423279,0.0008127383,0.0003411688,0.0001415782,0.00009841632,0.00112348,0.00000254539],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000759741,"about_ca_system_score_gemma":0.001852195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001510682,"about_ca_topic_score_gemma":0.01259555,"domain_scores_codex":[0.9940017,0.001183437,0.003531582,0.000299635,0.0005889401,0.0003946402],"domain_scores_gemma":[0.9940221,0.002729548,0.002098924,0.0002151084,0.0005714588,0.0003628127],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9181847,0.03946418,0.03075932,0.00004165727,0.0007798449,0.0009220884,0.001870481,0.0005196083,0.000271083,0.00004862103,0.0006971373,0.006441273],"study_design_scores_gemma":[0.906879,0.03875348,0.04955614,0.0002830424,0.001634811,0.0002513759,0.0009871121,0.0002199236,0.0002397612,0.00005367721,0.0009964887,0.0001451626],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9858698,0.0002665858,0.00004282799,0.008674954,0.001252943,0.003511969,0.00001629704,0.000006857158,0.0003577776],"genre_scores_gemma":[0.9975012,0.00008998977,0.0003949611,0.001228998,0.0004643607,0.0001167498,0.00000483456,0.0000234795,0.0001754273],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01879682,"threshold_uncertainty_score":0.7028614,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1711947335079127,"score_gpt":0.5148333912451809,"score_spread":0.3436386577372682,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}