{"id":"W3010161595","doi":"10.1200/jco.2007.25.18_suppl.1003","title":"A randomized, double-blind phase II study of the oral tyrosine kinase inhibitor (TKI) axitinib (AG-013736) in combination with docetaxel (DOC) compared to DOC plus placebo (PL) in metastatic breast cancer (MBC)","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Cancer Treatment and Pharmacology","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Notre-Dame","funders":"","keywords":"Medicine; Docetaxel; Internal medicine; Taxane; Adverse effect; Gastroenterology; Placebo; Nausea; Neutropenia; Febrile neutropenia; Stomatitis; Metastatic breast cancer; Anthracycline; Chemotherapy; Breast cancer; Pharmacology; Oncology; Cancer; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002317027,0.002446512,0.003934925,0.000639199,0.0006263374,0.001286655,0.001416085,0.001976781,0.008489011],"category_scores_gemma":[0.002295399,0.00133293,0.001466751,0.0006670223,0.002297589,0.001269788,0.0005197037,0.003714269,0.001669847],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001048367,"about_ca_system_score_gemma":0.002317313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001093559,"about_ca_topic_score_gemma":0.002346029,"domain_scores_codex":[0.999083,0.000513565,0.00005554781,0.0001420364,0.00006789601,0.0001379738],"domain_scores_gemma":[0.9983478,0.0004916406,0.0003182545,0.000144941,0.00009519878,0.0006022408],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9760327,0.01457314,0.000215534,0.0002400427,0.0002230744,0.00001934018,0.00003458909,0.0001575566,0.002996095,0.00005350308,0.0003336181,0.005120772],"study_design_scores_gemma":[0.8961126,0.102304,0.0005767835,0.000009977193,0.0001288315,0.0000157632,0.00001124965,0.000222352,0.0003053852,0.0000719319,0.0002327116,0.000008350197],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9836653,0.00182053,0.0009144495,0.0005422927,0.000826182,0.009090373,0.001207561,0.0001767127,0.001756583],"genre_scores_gemma":[0.9750518,0.002211623,0.002428038,0.0009365768,0.0008119438,0.01235451,0.001191144,0.00005038309,0.004963974],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008489011,"threshold_uncertainty_score":0.02839857,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1711947335079127,"score_gpt":0.5148333912451809,"score_spread":0.3436386577372682,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}