{"id":"W3010256122","doi":"10.1074/mcp.r120.001941","title":"Proximity Dependent Biotinylation: Key Enzymes and Adaptation to Proteomics Approaches","year":2020,"lang":"en","type":"review","venue":"Molecular & Cellular Proteomics","topic":"Biotin and Related Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":208,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sinai Health System; Lunenfeld-Tanenbaum Research Institute","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Government of Canada; Ontario Genomics; Genome Canada","keywords":"Protein Data Bank (RCSB PDB); Biotinylation; Proteome; Proteomics; Context (archaeology); Computational biology; Biochemistry; Biology; Enzyme; Computer science; Bioinformatics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001967944,0.001696862,0.001708043,0.003432666,0.0003916768,0.001854711,0.001903384,0.002026118,0.002618824],"category_scores_gemma":[0.001778197,0.0009951717,0.0008589006,0.004032414,0.001411257,0.003423317,0.001418994,0.004512287,0.004594773],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00192555,"about_ca_system_score_gemma":0.001536052,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001272778,"about_ca_topic_score_gemma":0.001295814,"domain_scores_codex":[0.9991037,0.0001602792,0.0001002132,0.0002422751,0.0003063044,0.00008714411],"domain_scores_gemma":[0.9991473,0.0004583892,0.00007879594,0.00005021268,0.0002077983,0.00005736771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001135391,0.00009645331,0.0002132798,0.02594218,0.0001098418,0.0003588614,0.000133765,0.0008893288,0.01433164,0.02808058,0.02432292,0.9054076],"study_design_scores_gemma":[0.000007420815,0.00005511109,0.0001841398,0.001075001,0.00003976452,0.0006125005,0.00002965355,0.000109449,0.004663106,0.00283684,0.9903617,0.00002534642],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001928846,0.9951518,0.002143133,0.0003794901,0.0003891361,0.00001399585,0.00003612314,0.00003375544,0.001659788],"genre_scores_gemma":[0.0008242496,0.9957585,0.001693936,0.0003433659,0.0001802932,0.00002439464,0.00007391257,0.00001081359,0.001090481],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003432666,"threshold_uncertainty_score":0.01397085,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04644855001783623,"score_gpt":0.2539493751721539,"score_spread":0.2075008251543177,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}