{"id":"W3010268681","doi":"10.3389/fgene.2020.00174","title":"Recruitment of an Activated Gene to the Yeast Nuclear Pore Complex Requires Sumoylation","year":2020,"lang":"en","type":"article","venue":"Frontiers in Genetics","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of General Medical Sciences; University of California, Davis; University of Alberta","keywords":"SUMO protein; Biology; Nuclear pore; Gene; Locus (genetics); Regulator; Chromatin; Gene expression; Cell biology; Regulation of gene expression; Ubiquitin; Genetics; Nucleus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001067298,0.0001071884,0.0001260075,0.00002837826,0.0000421275,0.00001284342,0.0002632685,0.00008807651,0.00001436256],"category_scores_gemma":[0.00003782199,0.00009320997,0.00003871647,0.0001371622,0.00004808068,0.000002530509,0.0001069354,0.00006554033,0.00000347134],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001370825,"about_ca_system_score_gemma":0.00003270113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006247761,"about_ca_topic_score_gemma":0.000008220908,"domain_scores_codex":[0.99919,0.00009117201,0.0001968804,0.0002387574,0.0001224818,0.0001607025],"domain_scores_gemma":[0.9995024,0.000002064369,0.00007138767,0.0002793639,0.00004533668,0.00009942755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000187414,0.00003837456,0.00185706,0.00001342498,0.00002574617,0.000002026116,0.0007751103,0.001159249,0.9679328,0.00001882501,0.00700865,0.02098131],"study_design_scores_gemma":[0.0003580565,0.0006148737,0.00555206,0.000008173492,0.00001057297,0.000002215801,0.000441612,0.002440323,0.8414657,0.00006787638,0.1488884,0.000150237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944096,0.0003503679,0.003164116,0.0008791428,0.0001529967,0.0006090054,0.00007396064,0.00001030853,0.0003505537],"genre_scores_gemma":[0.9746602,0.0001161809,0.02386763,0.000880427,0.0001935669,0.00002112492,0.0002134013,0.00002440996,0.0000230179],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1418797,"threshold_uncertainty_score":0.3800992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0623753187544843,"score_gpt":0.2794707826008925,"score_spread":0.2170954638464082,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}