{"id":"W3010370531","doi":"10.1002/hep.31205","title":"Cilofexor, a Nonsteroidal FXR Agonist, in Patients With Noncirrhotic NASH: A Phase 2 Randomized Controlled Trial","year":2020,"lang":"en","type":"article","venue":"Hepatology","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":321,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Liver Centre; Muscular Dystrophy Canada; University of Toronto","funders":"","keywords":"Nonsteroidal; Agonist; Medicine; Randomized controlled trial; Internal medicine; Pharmacology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002750211,0.001392332,0.00250285,0.0004939013,0.0003746224,0.0009241729,0.0006997449,0.001785691,0.006951319],"category_scores_gemma":[0.002093583,0.0005852983,0.00154495,0.0004186233,0.0008586874,0.0009989467,0.000326701,0.001570898,0.0007499756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000564058,"about_ca_system_score_gemma":0.001151753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000618251,"about_ca_topic_score_gemma":0.001680016,"domain_scores_codex":[0.9992244,0.0004677873,0.00005861713,0.00009949927,0.00005514447,0.00009450276],"domain_scores_gemma":[0.9991471,0.0002534541,0.0002437742,0.00005980511,0.00007680323,0.0002190799],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9745466,0.004884573,0.0007030626,0.0009820663,0.0007548309,0.00005663041,0.00004134213,0.0001658155,0.002354835,0.00007672082,0.000823225,0.01461021],"study_design_scores_gemma":[0.9798127,0.01854111,0.0007750457,0.00002352748,0.0002135599,0.00002300887,0.000008559122,0.0001270298,0.0001297397,0.00003021729,0.0003103482,0.000005045324],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.970595,0.01470907,0.001082372,0.001632433,0.00086891,0.00661726,0.001526688,0.0002395835,0.002728719],"genre_scores_gemma":[0.9704592,0.008712596,0.002742301,0.002492787,0.0009545787,0.00925045,0.001901335,0.00003429253,0.003452468],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006951319,"threshold_uncertainty_score":0.02325451,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.013133113772877,"score_gpt":0.2621497445796389,"score_spread":0.2490166308067619,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}