{"id":"W3010385770","doi":"10.5430/jst.v10n1p19","title":"Detecting EGFR mutations (L858R, T790M) using allele specific multiplex sequencing: A comparison with Pyrosequencing and TruSeq","year":2020,"lang":"en","type":"article","venue":"Journal of Solid Tumors","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"T790M; Pyrosequencing; Concordance; Multiplex; Molecular biology; Medicine; Multiplex polymerase chain reaction; Mutation; Polymerase chain reaction; Biology; Genetics; Gene; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00472565,0.0007824723,0.0005291969,0.001538163,0.000254916,0.0008355197,0.0006146907,0.0007021142,0.0006063814],"category_scores_gemma":[0.004401435,0.0006363182,0.0004029895,0.0005983821,0.0006439992,0.0005623585,0.0007052261,0.000534353,0.0003360492],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002933457,"about_ca_system_score_gemma":0.0002287587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006562436,"about_ca_topic_score_gemma":0.001653105,"domain_scores_codex":[0.9947309,0.001499342,0.0002672625,0.00101544,0.002295285,0.0001917617],"domain_scores_gemma":[0.996983,0.001553712,0.0005377511,0.0002920712,0.0004444635,0.0001889254],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001078796,0.0001510514,0.02849487,0.0002759832,0.0001651681,0.0001692772,0.000447477,0.001431163,0.888878,0.000225366,0.0001385432,0.07854433],"study_design_scores_gemma":[0.00006344881,0.004384716,0.09045186,0.00006644821,0.0003465531,0.005118278,0.0002259595,0.0347772,0.8600876,0.0003858524,0.003963044,0.0001290374],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.924348,0.003730008,0.06992079,0.0001690724,0.00005350807,0.0001026888,0.0002478262,0.0003629434,0.001065159],"genre_scores_gemma":[0.8607466,0.002257398,0.1341675,0.0002083758,0.00007870561,0.0001376558,0.0004126224,0.00006951365,0.001921688],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00472565,"threshold_uncertainty_score":0.02499193,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07471580483948895,"score_gpt":0.3471576297941418,"score_spread":0.2724418249546529,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}