{"id":"W3010553707","doi":"10.1021/acs.orglett.0c00505","title":"Synthesis of a <i>meso</i>-Oxa-Diaminopimelic Acid Containing Peptidoglycan Pentapeptide and Coupling to the GlcNAc-<i>anhydro</i>-MurNAc Disaccharide","year":2020,"lang":"en","type":"article","venue":"Organic Letters","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Pentapeptide repeat; Peptidoglycan; Diaminopimelic acid; Chemistry; Disaccharide; Stereochemistry; Serine; Residue (chemistry); Biochemistry; Amino acid; Peptide; Cell wall; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009031931,0.0003100844,0.00021274,0.0001190838,0.000116583,0.0001782805,0.0001658823,0.0001988791,0.0008797374],"category_scores_gemma":[0.0001079366,0.0001197542,0.0001551387,0.0002084384,0.0001120102,0.0001571957,0.0002273228,0.0003924849,0.0005839151],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001424895,"about_ca_system_score_gemma":0.0002188046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001711175,"about_ca_topic_score_gemma":0.0002312453,"domain_scores_codex":[0.9999367,0.000008951818,0.000005414639,0.0000149258,0.00001586332,0.00001825208],"domain_scores_gemma":[0.9999418,0.000006692633,0.00001307941,0.000006004114,0.000006547888,0.00002575607],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003048991,0.000009963228,0.00005283441,0.00004442362,0.00000256047,0.0001502751,0.00002359235,0.0001091657,0.9972256,0.0001441926,0.00003514,0.002171755],"study_design_scores_gemma":[0.00001012216,0.0002031582,0.0007232644,0.000005154585,0.000006350645,0.0004364788,0.00001930445,0.0003486833,0.9938678,0.00007859028,0.004294561,0.000006603758],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9537867,0.001804656,0.0354063,0.0001676248,0.0001158139,0.0002132981,0.0007964268,0.0001492529,0.007559975],"genre_scores_gemma":[0.9605076,0.001530882,0.03276639,0.00008583615,0.00002175757,0.00008321652,0.0007249634,0.00005096913,0.004228351],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008797374,"threshold_uncertainty_score":0.002942979,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01230661977849359,"score_gpt":0.2009776770679985,"score_spread":0.1886710572895049,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}