{"id":"W3010614308","doi":"10.3390/metabo10030088","title":"Analysis and Simulation of Glioblastoma Cell Lines-Derived Extracellular Vesicles Metabolome","year":2020,"lang":"en","type":"article","venue":"Metabolites","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"National Research Council Canada","keywords":"Extracellular vesicles; Metabolome; Glioblastoma; Extracellular; Cell culture; Vesicle; Chemistry; Computational biology; Metabolomics; Cell biology; Biology; Cancer research; Bioinformatics; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001678672,0.0002036235,0.0003716677,0.0001049267,0.00004674756,0.00002566703,0.0001875577,0.0001117371,0.00005314483],"category_scores_gemma":[0.0002266269,0.0001991814,0.0002371845,0.0004952422,0.0001256284,0.00001092604,0.0001318134,0.00006785234,0.000007077879],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000220241,"about_ca_system_score_gemma":0.00002716289,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004815596,"about_ca_topic_score_gemma":0.000003033236,"domain_scores_codex":[0.9986678,0.0001310779,0.0003714031,0.0004475851,0.0001794892,0.0002025891],"domain_scores_gemma":[0.999109,0.00004064349,0.0001907529,0.0003480852,0.000119742,0.0001918028],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001409867,0.00007148063,0.01493941,0.00005567513,0.0003183925,0.000003970458,0.0001138639,0.008333432,0.9746913,0.00003655472,0.00001350485,0.00128138],"study_design_scores_gemma":[0.0004597892,0.0001141939,0.01490604,0.000002197402,0.0009248297,5.4445e-7,0.00007013502,0.01533817,0.963905,0.00003973125,0.00403419,0.000205192],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9474978,0.03608121,0.01604031,0.00007546125,0.00002667713,0.0001458909,0.00005962351,0.00002191502,0.0000511606],"genre_scores_gemma":[0.9963035,0.0002905822,0.002905435,0.0001228358,0.0001637165,0.000007502382,0.00008954604,0.00002778348,0.0000891255],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04880571,"threshold_uncertainty_score":0.812238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009989103980621005,"score_gpt":0.2416249980184491,"score_spread":0.2316358940378281,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}