{"id":"W3010627948","doi":"10.1016/j.nlm.2020.107208","title":"Habituation in high-throughput genetic model organisms as a tool to investigate the mechanisms of neurodevelopmental disorders","year":2020,"lang":"en","type":"review","venue":"Neurobiology of Learning and Memory","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Habituation; Biology; Zebrafish; Candidate gene; Drosophila melanogaster; Danio; Neuroscience; Model organism; Caenorhabditis elegans; Phenotype; Neurodevelopmental disorder; Genetics; Computational biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008531457,0.001448684,0.002144642,0.001439248,0.0002060447,0.0011485,0.001665038,0.001494481,0.002239289],"category_scores_gemma":[0.0005753406,0.0003824813,0.0006638128,0.001514602,0.0008743356,0.001233008,0.0008295549,0.003084157,0.001897681],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001012468,"about_ca_system_score_gemma":0.0008270899,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001429978,"about_ca_topic_score_gemma":0.002266992,"domain_scores_codex":[0.9997464,0.00004455418,0.00002362214,0.00004424305,0.0001151,0.00002605562],"domain_scores_gemma":[0.9996018,0.0001957284,0.00005962482,0.00002826096,0.00007885126,0.00003578473],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001651497,0.0001365622,0.0002420182,0.01132509,0.0001821826,0.0003210335,0.00004970356,0.001683997,0.03325781,0.01881245,0.03239304,0.9014309],"study_design_scores_gemma":[0.00004641922,0.0001617157,0.0009809346,0.001327681,0.0001986816,0.001083405,0.00002788344,0.0004858139,0.00972083,0.007698528,0.9782098,0.00005821548],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002816061,0.9957206,0.001897013,0.0002739484,0.0002781674,0.00001177112,0.00006183364,0.00006028082,0.001414837],"genre_scores_gemma":[0.001684563,0.994957,0.001462467,0.0002951343,0.0001431009,0.00002826064,0.0001309413,0.00001091552,0.001287675],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002239289,"threshold_uncertainty_score":0.007491171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01191782381881362,"score_gpt":0.2487553123273677,"score_spread":0.2368374885085541,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}