{"id":"W3011015209","doi":"10.1111/ajt.15851","title":"Desensitization using imlifidase and EndoS enables chimerism induction in allosensitized recipient mice","year":2020,"lang":"en","type":"article","venue":"American Journal of Transplantation","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Canadian Diabetes Association; Canadian Institutes of Health Research; Li Ka Shing Foundation","keywords":"Immunology; Medicine; Bone marrow; Desensitization (medicine); Haematopoiesis; Endoglycosidase; Biology; Stem cell; Internal medicine; Glycoprotein; Molecular biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006496722,0.0008372819,0.0006348299,0.0006810867,0.0002746918,0.0006036613,0.0007420509,0.0008000595,0.003197116],"category_scores_gemma":[0.0003124936,0.0002894287,0.0006609531,0.0002511413,0.0004709433,0.0006771319,0.0005464517,0.002867073,0.0009169718],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002739969,"about_ca_system_score_gemma":0.0002648939,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000263222,"about_ca_topic_score_gemma":0.0004561248,"domain_scores_codex":[0.9992862,0.000132853,0.00007834634,0.0001769009,0.0001270191,0.0001987033],"domain_scores_gemma":[0.99953,0.00008578179,0.000140542,0.0001229877,0.00002641752,0.00009421493],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004024472,0.0002138179,0.0001674487,0.00002682308,0.000009718512,0.0001223856,0.00004605155,0.0001120057,0.9968838,0.000422003,0.0000585603,0.001534837],"study_design_scores_gemma":[0.00007038435,0.0008957228,0.001598851,0.0000129915,0.00003924255,0.0006353962,0.00004945927,0.001311271,0.9932538,0.0001449368,0.00198036,0.000007764197],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895682,0.0005298886,0.00573399,0.0001655414,0.000102497,0.0001751944,0.000497826,0.0003506659,0.00287624],"genre_scores_gemma":[0.9918846,0.0003721161,0.002828302,0.0001121206,0.00003432572,0.0001040168,0.0004311994,0.00012702,0.004106393],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003197116,"threshold_uncertainty_score":0.0106954,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02394164000713412,"score_gpt":0.268712340751027,"score_spread":0.2447707007438928,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}