{"id":"W3011022719","doi":"10.1158/1078-0432.ccr-19-3797","title":"Small-Cell Carcinoma of the Ovary, Hypercalcemic Type–Genetics, New Treatment Targets, and Current Management Guidelines","year":2020,"lang":"en","type":"review","venue":"Clinical Cancer Research","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":170,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill Genome Centre; Jewish General Hospital; Princess Margaret Cancer Centre; BC Cancer Agency; Spinal Cord Injury BC; McGill University; McGill University Health Centre","funders":"H2020 European Research Council; National Cancer Institute; Canadian Institutes of Health Research; Cancer Research UK; U.S. Department of Defense","keywords":"SMARCA4; Biology; Cancer; Ovarian cancer; Chromatin remodeling; Cancer research; Genetics; Epigenetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000682419,0.0006251858,0.001084785,0.002444018,0.0002657312,0.0007847807,0.0008985213,0.001033181,0.00288849],"category_scores_gemma":[0.001093281,0.0002634532,0.0005448369,0.001976907,0.0004237417,0.001271749,0.0004803313,0.002214648,0.001487782],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009430297,"about_ca_system_score_gemma":0.001381423,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001955626,"about_ca_topic_score_gemma":0.004563813,"domain_scores_codex":[0.9997867,0.00004210557,0.00003808095,0.00003365829,0.00007701703,0.00002244376],"domain_scores_gemma":[0.9995161,0.0002338071,0.00006139608,0.00001265481,0.0001307969,0.0000452029],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005645149,0.00004694835,0.0002862721,0.009519095,0.00007481833,0.0003389911,0.00003500586,0.0003567591,0.0004543094,0.002665749,0.1111611,0.8750045],"study_design_scores_gemma":[0.0000182799,0.00003709021,0.0007980936,0.00591547,0.0001072959,0.00238493,0.00003958396,0.00008540577,0.0001069803,0.002133208,0.9883585,0.00001503028],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006638731,0.9971735,0.0001108234,0.001057721,0.0004336084,0.00000546117,0.00002589673,0.00001062275,0.001115961],"genre_scores_gemma":[0.0005042445,0.9970879,0.0002266903,0.0009651317,0.0005218844,0.000007949131,0.00009282293,0.000002194264,0.0005911604],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00288849,"threshold_uncertainty_score":0.009662986,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4798473550500737,"score_gpt":0.5424238971364708,"score_spread":0.06257654208639707,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}