{"id":"W3011099411","doi":"10.1021/acsami.0c01172","title":"Nanoporosity Stimulates Cell Spreading and Focal Adhesion Formation in Cells with Mutated Paxillin","year":2020,"lang":"en","type":"article","venue":"ACS Applied Materials & Interfaces","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Paxillin; Focal adhesion; Filopodia; Nanotopography; Cell biology; Cell adhesion; Materials science; Adhesion; Actin; CDC42; Lamellipodium; Cell migration; Cell; Biophysics; Phosphorylation; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008478379,0.0001569295,0.0001690035,0.00002867002,0.00005264475,0.00008140796,0.0000935592,0.0001030567,0.00004632498],"category_scores_gemma":[0.000006519618,0.0001348842,0.000007987601,0.00004924445,0.000024514,0.00001416568,0.0001147882,0.00006243838,0.00001885502],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001073358,"about_ca_system_score_gemma":0.000009737842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003428741,"about_ca_topic_score_gemma":0.0000249788,"domain_scores_codex":[0.9992185,0.00002569381,0.0002355238,0.00028643,0.00006918634,0.0001646321],"domain_scores_gemma":[0.9996967,0.000009017718,0.0001046569,0.0001116398,0.0000274109,0.00005054964],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003381541,0.00003170193,0.000008964713,0.00005257196,0.000009878891,0.000002681179,0.0002734763,0.000234028,0.9987212,0.0000305911,0.0001027421,0.0001940547],"study_design_scores_gemma":[0.0005476256,0.0003257856,0.00001626835,0.00002460725,0.00001390248,0.000005052978,0.0003100804,0.0001138031,0.9981682,0.00003954432,0.0002662257,0.0001689163],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987298,0.00009901213,0.0005245346,0.000102031,0.00007663647,0.0002560561,0.00002864149,0.00001723026,0.0001661114],"genre_scores_gemma":[0.999109,0.0001504195,0.0003050765,0.0001877088,0.00004588812,0.00001986588,0.0001315162,0.00002097824,0.00002953563],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005529672,"threshold_uncertainty_score":0.5500417,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008541764871060996,"score_gpt":0.2018068117063388,"score_spread":0.1932650468352778,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}