{"id":"W3011099411","doi":"10.1021/acsami.0c01172","title":"Nanoporosity Stimulates Cell Spreading and Focal Adhesion Formation in Cells with Mutated Paxillin","year":2020,"lang":"en","type":"article","venue":"ACS Applied Materials & Interfaces","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Paxillin; Focal adhesion; Filopodia; Nanotopography; Cell biology; Cell adhesion; Materials science; Adhesion; Actin; CDC42; Lamellipodium; Cell migration; Cell; Biophysics; Phosphorylation; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006561914,0.0002005147,0.0001755592,0.0001126101,0.0001041365,0.0001846694,0.0001117404,0.0002390399,0.0007193064],"category_scores_gemma":[0.000099216,0.0001299034,0.0001871225,0.00009792967,0.0001443291,0.0001375763,0.0001930664,0.0002252451,0.0001312196],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001604971,"about_ca_system_score_gemma":0.00006945081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000782901,"about_ca_topic_score_gemma":0.001065767,"domain_scores_codex":[0.9999021,0.00001020866,0.000007079174,0.00001684494,0.00003419889,0.0000295818],"domain_scores_gemma":[0.9999261,0.0000238663,0.00001728695,0.000006862242,0.000007719636,0.00001819514],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002019878,0.000004347665,0.00004810984,0.000006190349,0.000001248022,0.00001004197,0.00000430314,0.00002088675,0.9997763,0.000006243799,0.000002902659,0.00009941247],"study_design_scores_gemma":[0.00000516201,0.00017737,0.00418263,0.000001546388,0.000008012739,0.00006611608,0.00002997764,0.001026903,0.9942168,0.00001036138,0.0002714536,0.000003512418],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992119,0.0001521194,0.0003395179,0.00001636007,0.000004662842,0.000004229188,0.00004779999,0.000007661598,0.0002156927],"genre_scores_gemma":[0.9985723,0.0001575806,0.0006829516,0.00001927924,0.000003587464,0.00001198229,0.0001184506,0.000005192486,0.0004286998],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000782901,"threshold_uncertainty_score":0.002406299,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008541764871060996,"score_gpt":0.2018068117063388,"score_spread":0.1932650468352778,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}