{"id":"W3011145000","doi":"10.1002/ijc.32967","title":"Major multilevel molecular divergence between THP‐1 cells from different biorepositories","year":2020,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Leukemia and Lymphoma Society of Canada","keywords":"Biology; THP1 cell line; Myeloid leukemia; Cell culture; Loss of heterozygosity; Monocytic leukemia; Phenotype; Cancer research; Leukemia; Myeloid; Computational biology; Genetics; Molecular biology; Gene; Cell biology; Allele","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005678659,0.0001223299,0.0002758219,0.00008404695,0.00002412124,0.00004188122,0.0004376015,0.00006104053,0.0005500148],"category_scores_gemma":[0.0001018787,0.00009087716,0.0001621055,0.00006000666,0.00005965769,0.0001138537,0.0001369048,0.0003732838,0.00002431951],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003789187,"about_ca_system_score_gemma":0.0002725774,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003290611,"about_ca_topic_score_gemma":0.000006031811,"domain_scores_codex":[0.9982231,0.00003279371,0.0003954328,0.0001503611,0.001055371,0.0001429928],"domain_scores_gemma":[0.9986421,0.00009379381,0.0002386702,0.00008873269,0.0006686854,0.0002679535],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001016748,0.00007061912,0.2911929,0.00002128543,0.002253648,0.001180437,0.0007760156,0.00007727269,0.6752117,0.00005123863,0.007007478,0.0211407],"study_design_scores_gemma":[0.002822644,0.0002114299,0.2122077,0.0002097588,0.0002588718,0.00002041451,0.00007085114,0.0005239614,0.7711568,0.000205111,0.0121758,0.000136583],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9763239,0.001123359,0.007010984,0.01396822,0.001199678,0.00009563413,0.0001599145,0.00001124849,0.0001070603],"genre_scores_gemma":[0.9943507,0.0003079182,0.001050623,0.001101009,0.003050807,0.000003914817,0.00001151761,0.00001808199,0.0001054116],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09594514,"threshold_uncertainty_score":0.6022276,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02820173870952105,"score_gpt":0.3402679494682558,"score_spread":0.3120662107587348,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}