{"id":"W3011223442","doi":"10.1093/ndt/gfz294","title":"The impact of empagliflozin on kidney injury molecule-1: a subanalysis of the Effects of Empagliflozin on Cardiac Structure, Function, and Circulating Biomarkers in Patients with Type 2 Diabetes CardioLink-6 trial","year":2020,"lang":"en","type":"letter","venue":"Nephrology Dialysis Transplantation","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network; Mount Sinai Hospital; University of Toronto; Lunenfeld-Tanenbaum Research Institute; St. Michael's Hospital","funders":"Boehringer Ingelheim","keywords":"Empagliflozin; Medicine; Type 2 diabetes; Benzhydryl compounds; Renal function; Internal medicine; Cardiac function curve; Diabetes mellitus; Cardiology; Endocrinology; Heart failure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005266452,0.0005345244,0.002131599,0.000271233,0.0005233198,0.001448164,0.0007147957,0.005037153,0.00314761],"category_scores_gemma":[0.0134483,0.0003547181,0.001644992,0.0004890118,0.0004394877,0.0008590447,0.0004163276,0.004855763,0.001101548],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001513598,"about_ca_system_score_gemma":0.001485756,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002278266,"about_ca_topic_score_gemma":0.006608712,"domain_scores_codex":[0.9968972,0.00198104,0.0003033733,0.0002409227,0.0003865806,0.0001908398],"domain_scores_gemma":[0.9901,0.007164688,0.0009245627,0.0002794214,0.0006401114,0.0008913635],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.1523757,0.001340615,0.04500011,0.001666433,0.005551357,0.00301249,0.0002594495,0.0009958969,0.002757341,0.002233985,0.573062,0.2117446],"study_design_scores_gemma":[0.2694148,0.0201349,0.1983496,0.002449827,0.0168579,0.003425163,0.0005946628,0.008700923,0.004306232,0.01453562,0.4607914,0.0004389563],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.1389045,0.03054946,0.0008792679,0.7666878,0.02224155,0.0006085218,0.01255416,0.0002074454,0.02736736],"genre_scores_gemma":[0.2856604,0.007551858,0.002057749,0.6430959,0.04158806,0.001096696,0.003580482,0.00007641927,0.01529235],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.005266452,"threshold_uncertainty_score":0.027852,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00410406241820072,"score_gpt":0.2149903291600831,"score_spread":0.2108862667418824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}