{"id":"W3011223442","doi":"10.1093/ndt/gfz294","title":"The impact of empagliflozin on kidney injury molecule-1: a subanalysis of the Effects of Empagliflozin on Cardiac Structure, Function, and Circulating Biomarkers in Patients with Type 2 Diabetes CardioLink-6 trial","year":2020,"lang":"en","type":"letter","venue":"Nephrology Dialysis Transplantation","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network; Mount Sinai Hospital; University of Toronto; Lunenfeld-Tanenbaum Research Institute; St. Michael's Hospital","funders":"Boehringer Ingelheim","keywords":"Empagliflozin; Medicine; Type 2 diabetes; Benzhydryl compounds; Renal function; Internal medicine; Cardiac function curve; Diabetes mellitus; Cardiology; Endocrinology; Heart failure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002037093,0.0004209863,0.001323065,0.0004956663,0.00007591798,0.00001312638,0.0001497868,0.0003661554,0.000007075382],"category_scores_gemma":[0.0001738513,0.0002368062,0.0005946493,0.0008749344,0.0002381928,0.00004402531,0.0000187104,0.0004692608,5.777526e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009856598,"about_ca_system_score_gemma":0.000132808,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009340035,"about_ca_topic_score_gemma":0.00001312201,"domain_scores_codex":[0.9972382,0.0007373101,0.0006776862,0.0004638748,0.0005763638,0.0003066085],"domain_scores_gemma":[0.9978757,0.000715178,0.0006744206,0.000503861,0.0001649708,0.00006587802],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.05955207,0.0003360996,0.8803315,0.001942413,0.03260403,0.00001982346,0.0006290244,0.0002633448,0.00498777,0.000006656495,0.01702804,0.002299305],"study_design_scores_gemma":[0.02907624,0.01371988,0.9250991,0.0006050928,0.02741731,2.356586e-7,0.00001385052,0.0001466669,0.003344541,0.00008112031,0.0001667926,0.000329115],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946711,0.00008477949,0.000005858207,0.002747375,0.0002691942,0.001836523,0.0003212618,0.00001392179,0.00005000384],"genre_scores_gemma":[0.9878995,0.0001566891,0.0000165729,0.009790028,0.0001861922,0.00006377831,0.001839154,0.00004317155,0.000004864998],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04476772,"threshold_uncertainty_score":0.9656675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00410406241820072,"score_gpt":0.2149903291600831,"score_spread":0.2108862667418824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}