{"id":"W3011302422","doi":"10.3390/cells9030706","title":"Role of c-Jun N-terminal Kinase (JNK) in Obesity and Type 2 Diabetes","year":2020,"lang":"en","type":"review","venue":"Cells","topic":"Adipokines, Inflammation, and Metabolic Diseases","field":"Medicine","cited_by":256,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Insulin resistance; Type 2 diabetes; Diabetes mellitus; Endocrinology; Kinase; Medicine; Internal medicine; Proinflammatory cytokine; Obesity; Inflammation; Insulin; c-jun; Protein kinase A; Biology; Cell biology; Biochemistry; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004920001,0.0008823242,0.001211581,0.002123558,0.0003368173,0.0009665015,0.0008325597,0.0009485445,0.003987385],"category_scores_gemma":[0.0004337175,0.0002256419,0.000396922,0.001994507,0.0003877732,0.001049009,0.0008137682,0.00194625,0.002777371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004703056,"about_ca_system_score_gemma":0.0009639702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009280767,"about_ca_topic_score_gemma":0.001629471,"domain_scores_codex":[0.9998584,0.00002236042,0.00002172668,0.00002350716,0.00005607102,0.00001803569],"domain_scores_gemma":[0.9998079,0.00005785141,0.00003026415,0.000004931265,0.00006515347,0.00003382736],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001266169,0.0000914759,0.0001700468,0.01806968,0.00009664306,0.0002206615,0.00006321743,0.0002671902,0.002042599,0.003511663,0.02908482,0.9462554],"study_design_scores_gemma":[0.00002268286,0.0001046637,0.0007383416,0.002884089,0.0001156365,0.001001003,0.00004899342,0.00006732577,0.000384223,0.001724793,0.99289,0.00001819687],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006470564,0.9990605,0.00005388303,0.0001410748,0.0001626984,0.000002700644,0.00001007172,0.000004294264,0.0005000799],"genre_scores_gemma":[0.0004118099,0.9988785,0.00008503726,0.0001015337,0.000117978,0.000004127608,0.00002181714,7.906247e-7,0.0003783186],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003987385,"threshold_uncertainty_score":0.0133391,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01690616221539836,"score_gpt":0.2779811613536032,"score_spread":0.2610749991382048,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}