{"id":"W3011302422","doi":"10.3390/cells9030706","title":"Role of c-Jun N-terminal Kinase (JNK) in Obesity and Type 2 Diabetes","year":2020,"lang":"en","type":"review","venue":"Cells","topic":"Adipokines, Inflammation, and Metabolic Diseases","field":"Medicine","cited_by":256,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Insulin resistance; Type 2 diabetes; Diabetes mellitus; Endocrinology; Kinase; Medicine; Internal medicine; Proinflammatory cytokine; Obesity; Inflammation; Insulin; c-jun; Protein kinase A; Biology; Cell biology; Biochemistry; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009186348,0.0002122086,0.001278642,0.0001261016,0.00001418455,0.000007197652,0.0000813368,0.0001306904,0.000124912],"category_scores_gemma":[0.0001008765,0.0001698139,0.0001480443,0.0002267352,0.00006821381,0.00003536137,0.00004665446,0.0001455561,0.00005599253],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001974578,"about_ca_system_score_gemma":0.0002826608,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001023353,"about_ca_topic_score_gemma":0.000002861576,"domain_scores_codex":[0.9990287,0.00005879487,0.0003973961,0.0002300667,0.0001301566,0.0001548531],"domain_scores_gemma":[0.9993181,0.00006960009,0.0001823946,0.0002133554,0.00005137765,0.0001651265],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000133999,0.0001166215,0.0007375135,0.02650348,0.00006892098,0.00007125582,0.000111266,9.15832e-8,0.0001086796,0.00004761993,0.0004824767,0.9717387],"study_design_scores_gemma":[0.0002467714,0.00005906434,0.0009509195,0.004846709,0.001105763,0.000007609377,0.00001390307,0.000006192591,0.0002066602,0.00003198347,0.9923862,0.0001382594],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01204907,0.9861498,2.797852e-7,0.000008688523,0.0001143332,0.0004662503,0.00004006935,0.00001610545,0.00115543],"genre_scores_gemma":[0.0007838656,0.9982662,0.00007065794,0.00003656934,0.0002819802,0.00001418623,0.0001073772,0.00002381411,0.0004154079],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9919037,"threshold_uncertainty_score":0.6924808,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01690616221539836,"score_gpt":0.2779811613536032,"score_spread":0.2610749991382048,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}