{"id":"W3011332060","doi":"10.3389/fphar.2020.00296","title":"Novel Anti-Interleukin-1β Therapy Preserves Retinal Integrity: A Longitudinal Investigation Using OCT Imaging and Automated Retinal Segmentation in Small Rodents","year":2020,"lang":"en","type":"article","venue":"Frontiers in Pharmacology","topic":"Retinopathy of Prematurity Studies","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; McGill University; Hôpital Maisonneuve-Rosemont; Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; March of Dimes Foundation","keywords":"Retinal; Retinopathy of prematurity; Retina; Optical coherence tomography; Medicine; Retinal Disorder; Ophthalmology; Diabetic retinopathy; Pathology; Biology; Endocrinology; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005170228,0.0005197914,0.0004477173,0.0005216554,0.0002258412,0.0003082252,0.0003329913,0.0004407859,0.0007231179],"category_scores_gemma":[0.0002013312,0.0002392268,0.000425597,0.0001872548,0.0003773031,0.0005139864,0.0001811312,0.001155023,0.0002040684],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002463392,"about_ca_system_score_gemma":0.0002341039,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005529188,"about_ca_topic_score_gemma":0.001064638,"domain_scores_codex":[0.9997793,0.00002928944,0.00001890538,0.00006203082,0.00005228353,0.00005808896],"domain_scores_gemma":[0.9996356,0.00002670797,0.0001484547,0.00003856217,0.00006204593,0.00008854631],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0008318144,0.0009686068,0.0005930564,0.00006124125,0.00002212628,0.00006472808,0.00003880784,0.0001400076,0.9933671,0.00005170163,0.00007050976,0.00379032],"study_design_scores_gemma":[0.0001754443,0.02270654,0.01949034,0.00002742997,0.0001801182,0.0005750222,0.0001479077,0.002679965,0.9514984,0.00009882182,0.002389954,0.00003004511],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935289,0.001216145,0.003971435,0.00007658294,0.00004198352,0.0001216316,0.000349817,0.0001038159,0.0005898091],"genre_scores_gemma":[0.9806629,0.002212957,0.01099182,0.0001751581,0.00002963674,0.0004052,0.001081585,0.00007749724,0.004363156],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007231179,"threshold_uncertainty_score":0.002734303,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06973208550473307,"score_gpt":0.3394575921435419,"score_spread":0.2697255066388088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}