{"id":"W3011349461","doi":"10.1038/s41419-020-2371-x","title":"PRDM3 attenuates pancreatitis and pancreatic tumorigenesis by regulating inflammatory response","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; National Institutes of Health; Foundation for the National Institutes of Health; Fundo para o Desenvolvimento das Ciências e da Tecnologia; Universidade de Macau; National Natural Science Foundation of China; Vanderbilt University","keywords":"Pancreatitis; Carcinogenesis; Inflammation; Cancer research; Inflammatory response; Pancreatic cancer; Medicine; Cell biology; Internal medicine; Biology; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001667936,0.000324771,0.0003983739,0.0002672832,0.0001565696,0.0003459995,0.0001988232,0.0002442899,0.001311242],"category_scores_gemma":[0.0001181982,0.0001141864,0.0003426885,0.0002188334,0.0003027577,0.0002184538,0.0002408706,0.001086947,0.0002244686],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002167448,"about_ca_system_score_gemma":0.0003153049,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003747531,"about_ca_topic_score_gemma":0.0004651882,"domain_scores_codex":[0.9998515,0.00002297862,0.00001695246,0.00002842145,0.00003037022,0.00004980751],"domain_scores_gemma":[0.9998748,0.000009765071,0.00003551213,0.00001396902,0.00001348437,0.00005239096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001309425,0.00018025,0.0006712677,0.0001078437,0.00001533705,0.00005901016,0.00001833464,0.00009494687,0.9937413,0.00008655454,0.00009777181,0.003618021],"study_design_scores_gemma":[0.0002125122,0.00223362,0.01893613,0.0000263292,0.00007790937,0.000329766,0.0001038666,0.00176367,0.9709471,0.0001739709,0.00518369,0.00001145529],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933993,0.002753678,0.001901894,0.0002037428,0.00007182723,0.00003902923,0.0004913807,0.000179752,0.0009593922],"genre_scores_gemma":[0.9952857,0.001142064,0.001181271,0.0001018543,0.00001744542,0.00004865766,0.0004686634,0.00001946634,0.001734974],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001311242,"threshold_uncertainty_score":0.004386544,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007788629933141841,"score_gpt":0.2132766098193377,"score_spread":0.2054879798861959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}