{"id":"W3011349461","doi":"10.1038/s41419-020-2371-x","title":"PRDM3 attenuates pancreatitis and pancreatic tumorigenesis by regulating inflammatory response","year":2020,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; National Institutes of Health; Foundation for the National Institutes of Health; Fundo para o Desenvolvimento das Ciências e da Tecnologia; Universidade de Macau; National Natural Science Foundation of China; Vanderbilt University","keywords":"Pancreatitis; Carcinogenesis; Inflammation; Cancer research; Inflammatory response; Pancreatic cancer; Medicine; Cell biology; Internal medicine; Biology; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001083082,0.0001401948,0.0001181089,0.00001620091,0.0001082947,0.00004192161,0.00004886178,0.0000573271,0.00001138319],"category_scores_gemma":[0.0002373851,0.0001370617,0.00003469393,0.00003835456,0.00005000925,0.00000517461,0.00006676822,0.00003444042,0.000003168624],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004126202,"about_ca_system_score_gemma":0.00006182153,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007469454,"about_ca_topic_score_gemma":5.827034e-7,"domain_scores_codex":[0.9991783,0.00009482825,0.0001506821,0.0003312771,0.00008255772,0.0001623834],"domain_scores_gemma":[0.999179,0.00003199099,0.00005711642,0.0001512921,0.00003308167,0.0005475161],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005568485,0.00001673493,0.3092258,0.00008355306,0.00001206596,0.00001101389,0.00006810338,0.00001374558,0.6882658,0.00001217725,0.0006081178,0.00112601],"study_design_scores_gemma":[0.001833315,0.0005715385,0.384278,0.00003662715,0.0001801932,0.000002928132,0.0001451211,0.001475443,0.5891873,0.0004801983,0.02111787,0.0006915015],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850162,0.01394604,0.0003341222,0.0002878286,0.00001753537,0.0001469813,0.00005477049,0.00001479174,0.0001817199],"genre_scores_gemma":[0.997597,0.001179471,0.0003020842,0.0003322807,0.0001060943,0.00001697413,0.0001422927,0.00002035355,0.0003034789],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09907858,"threshold_uncertainty_score":0.5589213,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007788629933141841,"score_gpt":0.2132766098193377,"score_spread":0.2054879798861959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}