{"id":"W3011381142","doi":"10.1016/j.ekir.2020.02.913","title":"SUN-374 B-CELL DEPLETION AND RESPONSE IN A RANDOMIZED, CONTROLLED TRIAL OF OBINUTUZUMAB FOR PROLIFERATIVE LUPUS NEPHRITIS","year":2020,"lang":"en","type":"article","venue":"Kidney International Reports","topic":"Systemic Lupus Erythematosus Research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Roche (Canada)","funders":"","keywords":"Obinutuzumab; Medicine; Lupus nephritis; CD20; Belimumab; Monoclonal antibody; Monoclonal; Internal medicine; Immunology; B cell; Cancer research; Oncology; Antibody; B-cell activating factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001668709,0.0008314732,0.002002826,0.0002957013,0.000296353,0.0008489646,0.0007293727,0.0009970806,0.002614832],"category_scores_gemma":[0.002127268,0.0003753282,0.001510141,0.0003577841,0.0009439677,0.0005418417,0.0002925918,0.001962974,0.0002318334],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006805404,"about_ca_system_score_gemma":0.0008156644,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001088864,"about_ca_topic_score_gemma":0.002190339,"domain_scores_codex":[0.9989491,0.0006735444,0.00007230433,0.0001191372,0.00007363821,0.0001123566],"domain_scores_gemma":[0.9989688,0.0004061302,0.0002777049,0.00007181673,0.00005059689,0.000224846],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9792352,0.001974782,0.002324536,0.0008954327,0.002628063,0.00003867076,0.00003120512,0.0002538954,0.001497607,0.0001000789,0.0003930351,0.0106275],"study_design_scores_gemma":[0.9236294,0.05848013,0.01088893,0.0001184479,0.003797896,0.00007121561,0.00003895091,0.0009723559,0.0009997353,0.0002484008,0.0007290281,0.00002554522],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910387,0.006897433,0.0001472736,0.0003531169,0.000307323,0.0003583754,0.0002006192,0.00003510681,0.0006619158],"genre_scores_gemma":[0.9971873,0.001170581,0.0002187777,0.0003012936,0.000171605,0.0002959935,0.0001570865,0.000005099721,0.0004921585],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002614832,"threshold_uncertainty_score":0.008825064,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01837310336821344,"score_gpt":0.3042281764120002,"score_spread":0.2858550730437868,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}