{"id":"W3011417498","doi":"10.1016/j.jad.2020.03.030","title":"Comparative efficacy and tolerability of pharmacological treatments for the treatment of acute bipolar depression: A systematic review and network meta-analysis","year":2020,"lang":"en","type":"review","venue":"Journal of Affective Disorders","topic":"Bipolar Disorder and Treatment","field":"Medicine","cited_by":138,"is_retracted":false,"has_abstract":false,"ca_institutions":"Providence Health Care; Queen's University","funders":"","keywords":"Quetiapine; Olanzapine; Ziprasidone; Lurasidone; Aripiprazole; Fluoxetine; Escitalopram; Psychology; Placebo; Lamotrigine; Tolerability; Divalproex; Psychiatry; Sertraline; Bipolar disorder; Atypical antipsychotic; Internal medicine; Medicine; Adverse effect; Antipsychotic; Mania; Antidepressant; Mood; Schizophrenia (object-oriented programming); Epilepsy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004261027,0.0005498102,0.01251021,0.0001380029,0.00009356778,0.00001056815,0.0001256237,0.0001286579,0.00003024061],"category_scores_gemma":[0.00008124903,0.0002266917,0.004075878,0.0006291592,0.000196795,0.00004574819,0.00003319281,0.0001932369,3.256156e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001232781,"about_ca_system_score_gemma":0.0001369504,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001958787,"about_ca_topic_score_gemma":0.00002404176,"domain_scores_codex":[0.9969636,0.0008612315,0.001365751,0.0003424846,0.0002835753,0.0001833242],"domain_scores_gemma":[0.9947212,0.002468223,0.002142325,0.0002810022,0.0002239442,0.0001633381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.0002338967,0.001757406,0.0003740746,0.1006013,0.8288443,0.000005248527,0.0003255048,0.000004982432,3.879174e-7,0.00000390674,0.00002936588,0.06781961],"study_design_scores_gemma":[0.002384726,0.004672492,0.0007070797,0.008468647,0.9749928,0.00006814543,0.00004967306,0.00001580554,0.000003316557,0.00001475798,0.008486202,0.0001363985],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006546457,0.9906522,0.0002274963,0.000166848,0.00003154173,0.008642825,0.0001996103,0.000004298683,0.000009709599],"genre_scores_gemma":[0.002323575,0.9968183,0.000205146,0.00002677767,0.00002545245,0.0005424424,0.00002704164,0.00001940184,0.00001185984],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.1461485,"threshold_uncertainty_score":0.9244218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.106084486500962,"score_gpt":0.4231439703954498,"score_spread":0.3170594838944878,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}