{"id":"W3011460553","doi":"10.3389/fcell.2020.00151","title":"Histone Lysine Demethylases KDM5B and KDM5C Modulate Genome Activation and Stability in Porcine Embryos","year":2020,"lang":"en","type":"article","venue":"Frontiers in Cell and Developmental Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Fonds de recherche du Québec; Fonds Québécois de la Recherche sur la Nature et les Technologies; Natural Sciences and Engineering Research Council of Canada; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Biology; Histone; Embryo; Genome; Cell biology; Genetics; Computational biology; DNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001498025,0.0001538614,0.0001537991,0.0001841723,0.000125388,0.0002267271,0.0001353468,0.0002320085,0.0006611081],"category_scores_gemma":[0.0001544483,0.0001383187,0.0002181955,0.0000856658,0.0001333783,0.0001277134,0.0001817874,0.000269512,0.0001714088],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002670125,"about_ca_system_score_gemma":0.0001215638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009858327,"about_ca_topic_score_gemma":0.001149128,"domain_scores_codex":[0.9999017,0.00001419531,0.000009783987,0.00002842927,0.00002194844,0.00002400271],"domain_scores_gemma":[0.9999194,0.00001814768,0.0000261807,0.000008023339,0.00001131339,0.00001683721],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007234053,0.000003993197,0.0004547387,0.00002364338,0.000003271746,0.00001987167,0.00001362814,0.00004106526,0.9987338,0.00003250733,0.00001193502,0.0005892247],"study_design_scores_gemma":[0.00001317038,0.0002884555,0.04199894,0.00001667917,0.00003283919,0.0001833962,0.00007423144,0.001103462,0.9528653,0.00006479077,0.003347528,0.00001112812],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928679,0.002808769,0.002502877,0.00005184684,0.00001977383,0.00001378612,0.000411157,0.0000329155,0.001290942],"genre_scores_gemma":[0.9950912,0.0009235055,0.001408606,0.0000637227,0.000004344373,0.00001945277,0.0005550818,0.00001387954,0.001920224],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009858327,"threshold_uncertainty_score":0.00221163,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01308981073372907,"score_gpt":0.2294569718191097,"score_spread":0.2163671610853806,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}