{"id":"W3011555918","doi":"10.1016/j.cell.2020.02.048","title":"Long-Term Expansion of Pancreatic Islet Organoids from Resident Procr+ Progenitors","year":2020,"lang":"en","type":"article","venue":"Cell","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":198,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Key Research and Development Program of China; University of Toronto; Science and Technology Commission of Shanghai Municipality; Chinese Academy of Sciences; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; National Natural Science Foundation of China","keywords":"Biology; Islet; Organoid; Progenitor cell; Term (time); Progenitor; Cell biology; Internal medicine; Endocrinology; Immunology; Stem cell; Diabetes mellitus","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00004211254,0.0001218908,0.000315494,0.00003636899,0.00002534674,0.000007997131,0.00006336906,0.00007088342,0.001244741],"category_scores_gemma":[0.0001552515,0.00009815604,0.00007391999,0.0001617106,0.00004226898,0.00003908285,0.00003293938,0.00009667194,0.0002576473],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002426457,"about_ca_system_score_gemma":0.0001070293,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000311889,"about_ca_topic_score_gemma":3.95571e-7,"domain_scores_codex":[0.9991089,0.00003037125,0.0002545537,0.0002238129,0.0002349831,0.0001473815],"domain_scores_gemma":[0.9993555,0.00006549289,0.00008634608,0.0002225515,0.00007433591,0.0001957766],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002128345,0.00008891799,0.2753013,0.000418912,0.00004776516,0.00003323422,0.001007022,0.000001280842,0.7175579,0.000002675244,0.004985713,0.0003424251],"study_design_scores_gemma":[0.001512663,0.0004648659,0.07818514,0.0001437785,0.0002475673,0.000002350182,0.0002524815,0.00007593264,0.9186931,0.00001839781,0.0003034151,0.0001002761],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994877,0.0008237989,0.0001252456,0.000399806,0.0001183295,0.0003614947,0.000008860537,0.00007584596,0.003209596],"genre_scores_gemma":[0.9971054,0.00004015036,0.0004913064,0.0006459087,0.0003134128,0.00001573038,0.00006881676,0.00002235372,0.001296976],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2011352,"threshold_uncertainty_score":0.9996682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01776563509827902,"score_gpt":0.2380239742078867,"score_spread":0.2202583391096077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}