{"id":"W3011555918","doi":"10.1016/j.cell.2020.02.048","title":"Long-Term Expansion of Pancreatic Islet Organoids from Resident Procr+ Progenitors","year":2020,"lang":"en","type":"article","venue":"Cell","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":198,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Key Research and Development Program of China; University of Toronto; Science and Technology Commission of Shanghai Municipality; Chinese Academy of Sciences; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; National Natural Science Foundation of China","keywords":"Biology; Islet; Organoid; Progenitor cell; Term (time); Progenitor; Cell biology; Internal medicine; Endocrinology; Immunology; Stem cell; Diabetes mellitus","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007561936,0.0003748907,0.0006935443,0.0002877018,0.0002281063,0.0009260275,0.0005810944,0.0004977942,0.003190391],"category_scores_gemma":[0.0003329314,0.0001743,0.0005715452,0.0003635696,0.0002862274,0.0004757652,0.0006006477,0.00254233,0.001633116],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001977557,"about_ca_system_score_gemma":0.0002684268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003113167,"about_ca_topic_score_gemma":0.0005789514,"domain_scores_codex":[0.9995537,0.00006431876,0.00006713245,0.0001247783,0.00009137513,0.00009872368],"domain_scores_gemma":[0.9992938,0.0002369433,0.00006012203,0.0001475683,0.00006978336,0.0001916479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00108123,0.0003677222,0.0008928691,0.0001275113,0.0000238444,0.0003787414,0.0003074215,0.0003431795,0.9870837,0.0003760198,0.0006185166,0.008399228],"study_design_scores_gemma":[0.0001679306,0.001879616,0.00952821,0.00006104521,0.0001042001,0.0008924723,0.000345195,0.001827785,0.9692035,0.0001861118,0.01578071,0.00002324538],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9771079,0.003435916,0.009436284,0.00026521,0.0002457759,0.0001758551,0.002767916,0.0002496182,0.006315538],"genre_scores_gemma":[0.9738075,0.001104848,0.007341446,0.0002984526,0.00009695862,0.000189813,0.005265598,0.0001423784,0.01175315],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003190391,"threshold_uncertainty_score":0.01067293,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01776563509827902,"score_gpt":0.2380239742078867,"score_spread":0.2202583391096077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}